|
Glioma
|
|
0.810 |
GeneticVariation
|
BEFREE |
In conclusion, we found an association between rs1412829 and rs4977756 (9p21.3, CDKN2B-AS1) and global DNA methylation pattern in glioma, for which a trend was seen also in the TCGA glioblastoma dataset.
|
27780202 |
2016 |
|
Glioma
|
|
0.810 |
GeneticVariation
|
GWASDB |
Chromosome 7p11.2 (EGFR) variation influences glioma risk.
|
21531791 |
2011 |
|
Glioma
|
|
0.810 |
GeneticVariation
|
GWASDB |
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.
|
19578366 |
2009 |
|
Glioma
|
|
0.810 |
GeneticVariation
|
GWASCAT |
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.
|
19578366 |
2009 |
|
Glioma
|
|
0.810 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies five susceptibility loci for glioma.
|
19578367 |
2009 |
|
Central Nervous System Neoplasms
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.
|
19578366 |
2009 |
|
Central Nervous System Neoplasms
|
|
0.800 |
GeneticVariation
|
GWASDB |
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.
|
19578366 |
2009 |
|
Nasopharyngeal carcinoma
|
|
0.720 |
GeneticVariation
|
BEFREE |
In this study, in southern China, where NPC is endemic, a single nucleotide polymorphism (SNP) in the EBV-encoded <i>RPMS1</i> gene (locus 155391: G > A [G155391A]) and seven host SNPs (rs1412829, rs28421666, rs2860580, rs2894207, rs31489, rs6774494, and rs9510787) were confirmed to be significantly associated with NPC risk in 50 NPC cases versus 54 hospital-based controls with throat washing specimens and 1925 NPC cases versus 1947 hospital-based controls with buffy coat samples, respectively.
|
29221111 |
2017 |
|
Nasopharyngeal carcinoma
|
|
0.720 |
GeneticVariation
|
BEFREE |
Our results also provide support for associations reported from published NPC GWAS-rs6774494 (P = 1.5 × 10(-12); located in the MECOM gene region), rs9510787 (P = 5.0 × 10(-10); located in the TNFRSF19 gene region), and rs1412829/rs4977756/rs1063192 (P = 2.8 × 10(-8), P = 7.0 × 10(-7), and P = 8.4 × 10(-7), respectively; located in the CDKN2A/B gene region).
|
26545403 |
2016 |
|
Nasopharyngeal carcinoma
|
|
0.720 |
GeneticVariation
|
GWASDB |
A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci.
|
20512145 |
2010 |
|
Nasopharyngeal Neoplasms
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A GWAS Meta-analysis and Replication Study Identifies a Novel Locus within CLPTM1L/TERT Associated with Nasopharyngeal Carcinoma in Individuals of Chinese Ancestry.
|
26545403 |
2016 |
|
Glaucoma, Open-Angle
|
|
0.700 |
GeneticVariation
|
GWASDB |
Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma.
|
22570617 |
2012 |
|
Calcification of coronary artery
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.
|
22144573 |
2011 |
|
Glaucoma
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1.
|
21532571 |
2011 |
|
Nasopharyngeal Neoplasms
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci.
|
20512145 |
2010 |
|
Coronary Artery Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Likewise, three SNPs, rs1412829_G [0.84(0.72-0.97); p = 0.019], rs564398_C [0.81(0.70-0.94); p = 0.006], rs4977756_G [0.87(0.76-0.99); p = 0.036] were significantly associated with MI after multivariate adjustments for CAD, HTN and DM, while the other five displayed borderline associations.
|
29894795 |
2018 |
|
Myocardial Infarction
|
|
0.010 |
GeneticVariation
|
BEFREE |
Likewise, three SNPs, rs1412829_G [0.84(0.72-0.97); p = 0.019], rs564398_C [0.81(0.70-0.94); p = 0.006], rs4977756_G [0.87(0.76-0.99); p = 0.036] were significantly associated with MI after multivariate adjustments for CAD, HTN and DM, while the other five displayed borderline associations.
|
29894795 |
2018 |
|
Piebaldism
|
|
0.010 |
GeneticVariation
|
BEFREE |
The results indicated that four SNPs, CDKN2BAS rs4977756 (p = 0.036), rs1412829 (p = 0.037), rs2157719 (p = 0.018) and rs1063192 (p = 0.021), were associated with an increased susceptibility to PBTs, whereas the TERT rs2736100 was associated with a decreased risk (p = 0.018).
|
26014354 |
2015 |
|
Anaplastic astrocytoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Wrensch and colleagues provided further evidence to 2 risk loci (CDKN2B rs1412829 and RTEL1 rs6010620) for GBM and anaplastic astrocytoma.
|
20212223 |
2010 |
|
Grade III Childhood Astrocytoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Wrensch and colleagues provided further evidence to 2 risk loci (CDKN2B rs1412829 and RTEL1 rs6010620) for GBM and anaplastic astrocytoma.
|
20212223 |
2010 |
|
Adult Anaplastic Astrocytoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Wrensch and colleagues provided further evidence to 2 risk loci (CDKN2B rs1412829 and RTEL1 rs6010620) for GBM and anaplastic astrocytoma.
|
20212223 |
2010 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.010 |
GeneticVariation
|
BEFREE |
Of the 18 polymorphisms, the ADAMTS9, CDKAL1, CDKN2A/B-rs1412829, FTO, IGF2BP2, JAZF1, SLC30A8, TCF7L2, and WFS1 variants were associated with type 2 diabetes risk in our population.
|
18694974 |
2008 |