rs1416580204, MOK

N. diseases: 49
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE The current meta-analysis suggests that the RAGE Gly82Ser polymorphism is associated with an increased risk of CAD and IS, especially in the Chinese population. 27930580 2016
Diabetes Mellitus, Non-Insulin-Dependent
0.060 GeneticVariation BEFREE We aimed to investigate the roles of RAGE, AGEs and the Gly82Ser polymorphism of RAGE in mild cognitive impairment (MCI) among type 2 diabetes patients. 26745632 2016
Diabetes Mellitus, Non-Insulin-Dependent
0.060 GeneticVariation BEFREE The -429 T/C and Gly82Ser RAGE polymorphisms were found to be significantly associated with the development of macrovascular and microvascular complications, respectively, in T2DM subjects while -374A allele showed reduced risk towards the development of macrovascular complications. 24418399 2014
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE Qualified articles had case-control designs and investigated AGER four polymorphisms (T-429C, T-374A, Gly82Ser, G1704A) or circulating soluble RAGE (sRAGE) or endogenous secretory RAGE (esRAGE) levels associated with CAD. 23894685 2013
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE Is there any association between GLY82 ser polymorphism of rage gene and Turkish diabetic and non diabetic patients with coronary artery disease? 21947881 2012
Diabetes Mellitus, Non-Insulin-Dependent
0.060 GeneticVariation BEFREE We previously reported the association of the Z-2 allele of the promoter dinucleotide repeat in the Aldose reductase (ALR2) gene, the (CCTTT)₁₅ allele in the promoter of inductible nitric oxide synthase (iNOS) gene, and the (GT)₁₃ promoter polymorphism in the tumor necrosis factor β (TNFB) gene with an increased risk for diabetic retinopathy (DR), and the Gly82Ser polymorphism in the receptor for advanced glycation end products (RAGE) gene and the (GT)₉ allele of the TNFB gene with low-risk for DR in a hospital-based self-reported type 2 diabetes mellitus (T2DM) patients. 21067489 2010
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE The haplotype carrying the G82S variant of the RAGE gene was significantly associated with an increased risk of CAD, but not with HT patients. 20668462 2010
Diabetes Mellitus, Non-Insulin-Dependent
0.060 GeneticVariation BEFREE G82S and -429 T/C polymorphisms of RAGE were associated with the circulating levels of esRAGE but not with CAD in Chinese patients with T2DM. 19766904 2009
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE G82S and -429 T/C polymorphisms of RAGE were associated with the circulating levels of esRAGE but not with CAD in Chinese patients with T2DM. 19766904 2009
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE The +557G>A (G82S) showed strong tendency of association with coronary artery disease (coronary artery disease</span> vs. normal; GG: 75.2 vs. 69.8%, GA: 23.2 vs. 28.6%, AA: 1.6 vs. 1.6%, P=0.0524). 17172923 2007
Diabetes Mellitus, Non-Insulin-Dependent
0.060 GeneticVariation BEFREE This study aims to investigate the frequency of Gly82Ser polymorphism in exon 3 of the receptor for AGE (RAGE) gene and its association with DR in Asian Indian patients who have type II diabetes. 12477623 2003
Diabetes Mellitus, Non-Insulin-Dependent
0.060 GeneticVariation BEFREE Statistically significant differences in allele frequencies between the NIDDM and the nondiabetic groups were observed for the G82S and 2245G/A polymorphisms (P =.047 and .032, respectively). 11586486 2001
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.040 GeneticVariation BEFREE Association of RAGE gene Gly82Ser polymorphism with coronary artery disease and ischemic stroke: A systematic review and meta-analysis. 27930580 2016
Diabetic Retinopathy
CUI: C0011884
Disease: Diabetic Retinopathy
0.040 GeneticVariation BEFREE The findings suggest that the G82S polymorphism in the RAGE gene is associated with DR risk, and G82S was associated with circulating levels of sRAGE. 24303504 2013
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.040 GeneticVariation BEFREE This meta-analysis demonstrates that there is no association between the RAGE -429T/C, -374T/A and G82S polymorphisms and CHD. 23236395 2012
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.040 GeneticVariation BEFREE Is there any association between GLY82 ser polymorphism of rage gene and Turkish diabetic and non diabetic patients with coronary artery disease? 21947881 2012
Diabetic Retinopathy
CUI: C0011884
Disease: Diabetic Retinopathy
0.040 GeneticVariation BEFREE Among the nine loci (15 polymorphisms) screened, SNP rs2070600 (G82S) in the RAGE gene, showed significant association with DR (allelic P = 0.016, dominant model P = 0.012), compared to DNR. 21067572 2010
Diabetic Retinopathy
CUI: C0011884
Disease: Diabetic Retinopathy
0.040 GeneticVariation BEFREE Z+2 allele of ALR2, 13-repeat genotype of iNOS, 15-repeat genotype of TNF-β, genes were associated with susceptibility to DR. Gly82Ser polymorphisms of the RAGE gene were not associated with DR in the present study. 21067489 2010
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.040 GeneticVariation BEFREE The +557G>A (G82S) showed strong tendency of association with coronary artery disease (coronary artery disease</span> vs. normal; GG: 75.2 vs. 69.8%, GA: 23.2 vs. 28.6%, AA: 1.6 vs. 1.6%, P=0.0524). 17172923 2007
Diabetic Retinopathy
CUI: C0011884
Disease: Diabetic Retinopathy
0.040 GeneticVariation BEFREE Association of Gly82Ser polymorphism in the RAGE gene with diabetic retinopathy in type II diabetic Asian Indian patients. 12477623 2003
Coronary Arteriosclerosis
CUI: C0010054
Disease: Coronary Arteriosclerosis
0.030 GeneticVariation BEFREE Association of RAGE gene Gly82Ser polymorphism with coronary artery disease and ischemic stroke: A systematic review and meta-analysis. 27930580 2016
Diabetes
CUI: C0011847
Disease: Diabetes
0.030 GeneticVariation BEFREE The association between the RAGE G82S polymorphism, sRAGE and chronic periodontitis in Taiwanese individuals with and without diabetes. 25988707 2015
Diabetes Mellitus
CUI: C0011849
Disease: Diabetes Mellitus
0.030 GeneticVariation BEFREE The present study revealed that the RAGE G82S polymorphism was associated with chronic periodontitis in the non-DM group but not in the DM group. 25988707 2015
Coronary Arteriosclerosis
CUI: C0010054
Disease: Coronary Arteriosclerosis
0.030 GeneticVariation BEFREE Is there any association between GLY82 ser polymorphism of rage gene and Turkish diabetic and non diabetic patients with coronary artery disease? 21947881 2012
Coronary Arteriosclerosis
CUI: C0010054
Disease: Coronary Arteriosclerosis
0.030 GeneticVariation BEFREE The +557G>A (G82S) showed strong tendency of association with coronary artery disease (coronary artery disease</span> vs. normal; GG: 75.2 vs. 69.8%, GA: 23.2 vs. 28.6%, AA: 1.6 vs. 1.6%, P=0.0524). 17172923 2007