rs1611115, DBH

N. diseases: 16
Disease: Marijuana Abuse ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Marijuana Abuse
CUI: C0024809
Disease: Marijuana Abuse
0.010 GeneticVariation BEFREE We hypothesized that individuals with low activity DBH genotypes (rs1611115 CT/TT) are more sensitive to the influence of cannabis and cocaine on cognitive impulse control and functional connectivity in the limbic 'reward' circuit because they experience a drug induced hyperdopaminergic state compared to individuals with high activity DBH genotypes (rs1611115 CC). 26667034 2016