rs165774, COMT

N. diseases: 11
Disease: Depressive Symptoms ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Depressive Symptoms
CUI: C0086132
Disease: Depressive Symptoms
0.010 GeneticVariation BEFREE Women who carried at least one "A" allele (AA/AG) for both rs165774 and rs4680 single nucleotide polymorphisms were less likely to report depressive symptoms (compared with women with the GG genotype; p = 0.019 and p = 0.037, respectively), although moderation analysis did not support the hypotheses of an interaction with stressful life events (rs165774: odds ratio [OR] = 1.13, 95% CI 0.87-1.46, p = 0.347; rs4680: OR = 1.15, 95% CI 0.91-1.44, p = 0.238). 27347613 2016