rs16851720, RNF7

N. diseases: 5
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Liver Cirrhosis
CUI: C0023890
Disease: Liver Cirrhosis
0.810 GeneticVariation BEFREE Our study showed that PNPLA3 rs738409 and RNF7 rs16851720 confer an increased risk of developing liver fibrosis and cirrhosis in this Eastern European population, while the MERTK and PCSK7 SNPs are not associated with these conditions. 28338112 2017
Liver Cirrhosis
CUI: C0023890
Disease: Liver Cirrhosis
0.810 GeneticVariation GWASCAT Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection. 22841784 2012
Liver Cirrhosis
CUI: C0023890
Disease: Liver Cirrhosis
0.810 GeneticVariation GWASDB Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection. 22841784 2012
Hepatitis C
CUI: C0019196
Disease: Hepatitis C
0.700 GeneticVariation GWASCAT In the combined cohort of 2342 HCV-infected patients, the SNPs rs16851720 (in the total sample) and rs4374383 (in patients who received blood transfusions) were associated with fibrosis progression (P(combined) = 8.9 × 10(-9) and 1.1 × 10(-9), respectively). 22841784 2012
Fibrosis, Liver
CUI: C0239946
Disease: Fibrosis, Liver
0.010 GeneticVariation BEFREE Our study showed that PNPLA3 rs738409 and RNF7 rs16851720 confer an increased risk of developing liver fibrosis and cirrhosis in this Eastern European population, while the MERTK and PCSK7 SNPs are not associated with these conditions. 28338112 2017
Hepatitis C, Chronic
CUI: C0524910
Disease: Hepatitis C, Chronic
0.010 GeneticVariation BEFREE Triplex High-Resolution Melting Assay for the Simultaneous Assessment of IFNL3 rs12979860, ABCB11 rs2287622, and RNF7 rs16851720 Genotypes in Chronic Hepatitis C Patients. 28860020 2017
Cirrhosis
CUI: C1623038
Disease: Cirrhosis
0.010 GeneticVariation BEFREE Our study showed that PNPLA3 rs738409 and RNF7 rs16851720 confer an increased risk of developing liver fibrosis and cirrhosis in this Eastern European population, while the MERTK and PCSK7 SNPs are not associated with these conditions. 28338112 2017