rs16944, IL1B

N. diseases: 92
Disease: Depressive disorder ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Depressive disorder
CUI: C0011581
Disease: Depressive disorder
0.020 GeneticVariation BEFREE We also demonstrated that the presence of exposure to childhood adversity changed the direction of the rs16944 effect on depression phenotype. 26891860 2016
Depressive disorder
CUI: C0011581
Disease: Depressive disorder
0.020 GeneticVariation BEFREE Considering the inflammatory-depression link, and that women are twice as likely to experience depression compared to men, the current study (<i>N</i> = 475 university students) examined the moderating role of three independent cytokine single nucleotide polymorphisms (SNPs; IL-1β rs16944, IL-6 rs1800795 SNP, TNF-α rs1800629) in the relationship between early-life adversity and depressive symptoms, and whether these relations differed between males and females. 30967802 2019