Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
When COMT(LL) was combined with either glutathione S-transferase (GST) M1 null or with GSTP1 Ile-105-Val/Val-105-Val (intermediate/low activity, respectively) genotypes, the risk for developing postmenopausal breast cancer was also significantly increased.
|
9407957 |
1997 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
When COMT(LL) was combined with either glutathione S-transferase (GST) M1 null or with GSTP1 Ile-105-Val/Val-105-Val (intermediate/low activity, respectively) genotypes, the risk for developing postmenopausal breast cancer was also significantly increased.
|
9407957 |
1997 |
Carcinoma of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
In this study we have addressed the possible role of the Ile105Val GSTP1 polymorphism in lung cancer susceptibility.
|
10334644 |
1999 |
Malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
In this study we have addressed the possible role of the Ile105Val GSTP1 polymorphism in lung cancer susceptibility.
|
10334644 |
1999 |
Primary malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
In this study we have addressed the possible role of the Ile105Val GSTP1 polymorphism in lung cancer susceptibility.
|
10334644 |
1999 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Association between survival after treatment for breast cancer and glutathione S-transferase P1 Ile105Val polymorphism.
|
11059750 |
2000 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
Association between survival after treatment for breast cancer and glutathione S-transferase P1 Ile105Val polymorphism.
|
11059750 |
2000 |
Carcinoma of bladder
|
|
0.080 |
GeneticVariation
|
BEFREE |
We investigated the effect of the GSTM1 and GSTT1 null genotypes, and GSTP1 313 A/G polymorphism on bladder cancer susceptibility in a case control study of 121 bladder cancer patients, and 121 age- and sex-matched controls of the Turkish population.
|
11757669 |
2001 |
Malignant neoplasm of urinary bladder
|
|
0.080 |
GeneticVariation
|
BEFREE |
We investigated the effect of the GSTM1 and GSTT1 null genotypes, and GSTP1 313 A/G polymorphism on bladder cancer susceptibility in a case control study of 121 bladder cancer patients, and 121 age- and sex-matched controls of the Turkish population.
|
11757669 |
2001 |
Bladder Neoplasm
|
|
0.070 |
GeneticVariation
|
BEFREE |
We investigated the effect of the GSTM1 and GSTT1 null genotypes, and GSTP1 313 A/G polymorphism on bladder cancer susceptibility in a case control study of 121 bladder cancer patients, and 121 age- and sex-matched controls of the Turkish population.
|
11757669 |
2001 |
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The GSTP1 Ile(105)Val polymorphism is associated in a dose-dependent fashion with increased survival of patients with advanced colorectal cancer receiving 5-FU/oxaliplatin chemotherapy.
|
12072547 |
2002 |
Malignant neoplasm of colon and/or rectum
|
|
0.080 |
GeneticVariation
|
BEFREE |
The GSTP1 Ile(105)Val polymorphism is associated in a dose-dependent fashion with increased survival of patients with advanced colorectal cancer receiving 5-FU/oxaliplatin chemotherapy.
|
12072547 |
2002 |
Adenocarcinoma of prostate
|
|
0.010 |
GeneticVariation
|
BEFREE |
I105V polymorphism and promoter methylation of the GSTP1 gene in prostate adenocarcinoma.
|
12010858 |
2002 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
Trends in the association between urinary ITC and breast cancer were more consistent with homozygous deletion of GSTM1 or GSTT1, the AAgenotype of GSTP1 (A313G), or with the C allele of NADPH quinine oxidoreductase (C609T), although interactions were not statistically significant.
|
12873994 |
2003 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Trends in the association between urinary ITC and breast cancer were more consistent with homozygous deletion of GSTM1 or GSTT1, the AAgenotype of GSTP1 (A313G), or with the C allele of NADPH quinine oxidoreductase (C609T), although interactions were not statistically significant.
|
12873994 |
2003 |
Glioma
|
|
0.040 |
GeneticVariation
|
BEFREE |
There was evidence of supermultiplicativity of the joint effect of GSTP1 I105V and CYP2E1 RsaI variants on both glioma and acoustic neuroma, even following adjustment of estimates toward a common prior distribution using hierarchical regression models.
|
12540498 |
2003 |
Schizophrenia
|
|
0.020 |
GeneticVariation
|
BEFREE |
This study is aimed to test the association between the coding sequence functional polymorphism (Ile105Val) of glutathione S-transferase P gene (GSTP1) and schizophrenia in the Korean population.
|
12691788 |
2003 |
Maternal hypertension
|
|
0.010 |
GeneticVariation
|
BEFREE |
We therefore performed an association study of the Ile105Val variant comparing 131 patients with HP and 327 normal pregnant controls in Japan.
|
14719182 |
2003 |
Pregnancy associated hypertension
|
|
0.010 |
GeneticVariation
|
BEFREE |
We therefore performed an association study of the Ile105Val variant comparing 131 patients with HP and 327 normal pregnant controls in Japan.
|
14719182 |
2003 |
Parkinson Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
We tested for associations between genotypes of GSTM1(homozygous deletion vs. non-deleted), GSTT1(homozygous deletion vs. non-deleted), and GSTP1 (Ile104Val and Ala113Val) and PD in a case-control study of 214 idiopathic PD cases and 330 age- and gender-matched, unrelated controls of Caucasian ethnicity.
|
12524158 |
2003 |
Childhood Leukemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
The role of methylenetetrahydrofolate reductase (MTHFR C677T), glutathione S-transferases (GSTM1 and GSTT1 null, GSTP1 Ile105Val), and cytochromes p450 (CYP1A1*2A) genotypes in the etiology of childhood leukemia was simultaneously investigated.
|
12827651 |
2003 |
Acoustic Neuroma
|
|
0.010 |
GeneticVariation
|
BEFREE |
There was evidence of supermultiplicativity of the joint effect of GSTP1 I105V and CYP2E1 RsaI variants on both glioma and acoustic neuroma, even following adjustment of estimates toward a common prior distribution using hierarchical regression models.
|
12540498 |
2003 |
Primary malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
In a population-based case-cohort study where cases and the subcohort sample were matched on duration of smoking, we investigated the occurrence of lung cancer and histological subtypes of lung cancer in relation to deletion polymorphism in both GSTM1 and GSTT1, single nucleotide polymorphisms (SNPs) in GSTP1 (Ile105Val and Ala114Val) and a 3 base pair deletion polymorphism in GSTM3.
|
15069685 |
2004 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
Deletion polymorphisms in the genes GSTM1 and GSTT1 and a base transition polymorphism at codon 105 (Ile-->Val) in GSTP1 were investigated in relation to breast cancer risk.
|
15342448 |
2004 |
Asthma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The polymorphism c.342A>G (p.I105V) in GSTP1 has previously been suggested as a risk factor for asthma.
|
15300848 |
2004 |