|
Malignant neoplasm of testis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The results of the multivariate analysis showed that the presence of variant alleles of GSTP1 (rs1695) together with a smoking habit and a family history of cancer accounted for a 15.9% risk of developing TCa in the Chilean population.
|
31107374 |
2019 |
|
Squamous cell carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
There are several meta-analyses on the genetic relationship between the rs1695 polymorphism within the GSTP1 (glutathione S-transferase pi 1) gene and the risk of different SCC (squamous cell carcinoma) diseases, such as ESCC (oesophageal SCC), HNSCC (head and neck SCC), LSCC (lung SCC), and SSCC (skin SCC).
|
30665373 |
2019 |
|
TARSAL-CARPAL COALITION SYNDROME
|
|
0.010 |
GeneticVariation
|
BEFREE |
This study indicated that GSTP1 gene 313 A/G (rs1695) polymorphism increased the susceptibility to BCa, particularly to TCC.
|
31454540 |
2019 |
|
Malignant Testicular Germ Cell Tumor
|
|
0.010 |
GeneticVariation
|
BEFREE |
The results of the multivariate analysis showed that the presence of variant alleles of GSTP1 (rs1695) together with a smoking habit and a family history of cancer accounted for a 15.9% risk of developing TCa in the Chilean population.
|
31107374 |
2019 |
|
Vomiting
|
|
0.010 |
GeneticVariation
|
BEFREE |
GSTP1 c.313A>G genotype was recently described as a predictor of vomiting related to high-dose cisplatin.
|
30870506 |
2019 |
|
Heart failure
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, carriers of at least one variant <i>GSTP1</i>∗Val (rs1695) allele were at 1.7-fold increased HF risk than <i>GSTP1</i>∗Ile/Ile carriers (<i>p</i> = 0.031), which was higher when combined with the variant <i>GSTA1</i>∗B allele (OR = 2.2, <i>p</i> = 0.034).
|
31275451 |
2019 |
|
Nausea and vomiting
|
|
0.010 |
GeneticVariation
|
BEFREE |
Cost-minimization analysis of GSTP1c.313A>G genotyping for the prevention of cisplatin-induced nausea and vomiting: A Bayesian inference approach.
|
30870506 |
2019 |
|
Nausea
|
|
0.010 |
GeneticVariation
|
BEFREE |
GSTP1 c.313A>G genotyping may reduce the use of preventive support for chemotherapy induced nausea and lower the overall cost of treatment.
|
30870506 |
2019 |
|
Congestive heart failure
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, carriers of at least one variant <i>GSTP1</i>∗Val (rs1695) allele were at 1.7-fold increased HF risk than <i>GSTP1</i>∗Ile/Ile carriers (<i>p</i> = 0.031), which was higher when combined with the variant <i>GSTA1</i>∗B allele (OR = 2.2, <i>p</i> = 0.034).
|
31275451 |
2019 |
|
Pneumonitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
GSTP1 Ile105Val polymorphism might be associated with the risk of radiation pneumonitis among lung cancer patients in Chinese population: A prospective study.
|
29556330 |
2018 |
|
Coronary Artery Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Logistic regression analysis of the data revealed the null genotype of GSTM1 and the GG genotype of the GSTP1 (313A/G) gene were associated with an approximately twofold enhanced risk of developing CAD, whereas GSTT1(-) plays a defensive role against CAD development in north Indians.
|
30039864 |
2018 |
|
Agranulocytosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
In conclusion, the GSTP1 rs1695 gene polymorphism is associated with granulocytopenia induced by platinum-based drugs.
|
30238837 |
2018 |
|
Alzheimer Disease, Late Onset
|
|
0.010 |
GeneticVariation
|
BEFREE |
We investigated the association of GSTM1 and GSTT1 null deletion and GSTP1 313 A/G polymorphisms and the risk of AD in an Iranian population.
|
29072550 |
2018 |
|
Rhinitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
To evaluate whether polymorphisms of IL4R (rs1805015), IL13 (rs20541), IL17A (rs2275913) and GSTP1 (rs1695) genes are associated with rhinitis and/or asthma in adults of Portuguese ancestry.
|
27561723 |
2018 |
|
Gastritis, Atrophic
|
|
0.010 |
GeneticVariation
|
BEFREE |
There is a multifarious interaction between the DNA repair gene <i>ERCC5</i> SNPs (rs2094258 and rs873601) and the metabolic gene <i>GSTP1</i> rs1695, which may form the basis for various inter-individual susceptibilities to AG.
|
29434449 |
2018 |
|
Granulocytopenic disorder
|
|
0.010 |
GeneticVariation
|
BEFREE |
In conclusion, the GSTP1 rs1695 gene polymorphism is associated with granulocytopenia induced by platinum-based drugs.
|
30238837 |
2018 |
|
Diabetic Nephropathy
|
|
0.010 |
GeneticVariation
|
BEFREE |
The purpose of this case-control study was to investigate the possible role of GSTM1 and GSTT1 deletion polymorphisms, and Single Nucleotide Polymorphism (SNP), GSTP1 313 A > G (Ile105Val), in DN susceptibility.
|
29981844 |
2018 |
|
Occupational Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
Ile105Val (rs1695) in glutathione S-transferase P1 (GSTP1) gene influences cytological toxicity and modulates the risk to occupational diseases.
|
28153749 |
2017 |
|
Acute pancreatitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The presence of GSTM1 is associated with increased susceptibility for AP, and the GSTP1 Val105Ile SNP is associated with an increased risk for AP in men.
|
27984487 |
2017 |
|
Influenza-like illness
|
|
0.010 |
GeneticVariation
|
BEFREE |
Mutant types of rs1041983 (N-acetyltransferase 2 gene, NAT2) had a synergetic effect with passive smoking on ILI frequency, while mutant types of rs1695 (glutathione S-transferase P1 gene, GSTP1) had an antagonistic effect.
|
28259080 |
2017 |
|
Influenza-like symptoms
|
|
0.010 |
GeneticVariation
|
BEFREE |
Mutant types of rs1041983 (N-acetyltransferase 2 gene, NAT2) had a synergetic effect with passive smoking on ILI frequency, while mutant types of rs1695 (glutathione S-transferase P1 gene, GSTP1) had an antagonistic effect.
|
28259080 |
2017 |
|
Obesity
|
|
0.010 |
GeneticVariation
|
BEFREE |
Impact of the Ile105Val Polymorphism of the Glutathione S-transferase P1 (GSTP1) Gene on Obesity and Markers of Cardiometabolic Risk in Young Adult Population.
|
28561194 |
2017 |
|
Febrile Neutropenia
|
|
0.010 |
GeneticVariation
|
BEFREE |
Among Japanese women who received epirubicin and cyclophosphamide as perioperative chemotherapy for early breast cancer, those with the A/A genotype of the GSTP1 polymorphism (rs1695) were more likely to have FN.
|
25008867 |
2016 |
|
Myeloproliferative disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Among a panel of polymorphisms in genes related to oxidative stress, CAT-262 C>T, GPX1 Pro198Leu and GSTP1 Ile105Val influence the risk of developing BCR-ABL negative myeloproliferative neoplasms.
|
27077777 |
2016 |
|
Ankylosing spondylitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association of GSTM1, GSTT1, GSTP1-ILE105VAL and ACE I/D polymorphisms with ankylosing spondylitis.
|
26186891 |
2016 |