|
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
When COMT(LL) was combined with either glutathione S-transferase (GST) M1 null or with GSTP1 Ile-105-Val/Val-105-Val (intermediate/low activity, respectively) genotypes, the risk for developing postmenopausal breast cancer was also significantly increased.
|
9407957 |
1997 |
|
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
When COMT(LL) was combined with either glutathione S-transferase (GST) M1 null or with GSTP1 Ile-105-Val/Val-105-Val (intermediate/low activity, respectively) genotypes, the risk for developing postmenopausal breast cancer was also significantly increased.
|
9407957 |
1997 |
|
Carcinoma of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
In this study we have addressed the possible role of the Ile105Val GSTP1 polymorphism in lung cancer susceptibility.
|
10334644 |
1999 |
|
Malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
In this study we have addressed the possible role of the Ile105Val GSTP1 polymorphism in lung cancer susceptibility.
|
10334644 |
1999 |
|
Primary malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
In this study we have addressed the possible role of the Ile105Val GSTP1 polymorphism in lung cancer susceptibility.
|
10334644 |
1999 |
|
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Association between survival after treatment for breast cancer and glutathione S-transferase P1 Ile105Val polymorphism.
|
11059750 |
2000 |
|
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
Association between survival after treatment for breast cancer and glutathione S-transferase P1 Ile105Val polymorphism.
|
11059750 |
2000 |
|
Carcinoma of bladder
|
|
0.080 |
GeneticVariation
|
BEFREE |
We investigated the effect of the GSTM1 and GSTT1 null genotypes, and GSTP1 313 A/G polymorphism on bladder cancer susceptibility in a case control study of 121 bladder cancer patients, and 121 age- and sex-matched controls of the Turkish population.
|
11757669 |
2001 |
|
Malignant neoplasm of urinary bladder
|
|
0.080 |
GeneticVariation
|
BEFREE |
We investigated the effect of the GSTM1 and GSTT1 null genotypes, and GSTP1 313 A/G polymorphism on bladder cancer susceptibility in a case control study of 121 bladder cancer patients, and 121 age- and sex-matched controls of the Turkish population.
|
11757669 |
2001 |
|
Bladder Neoplasm
|
|
0.070 |
GeneticVariation
|
BEFREE |
We investigated the effect of the GSTM1 and GSTT1 null genotypes, and GSTP1 313 A/G polymorphism on bladder cancer susceptibility in a case control study of 121 bladder cancer patients, and 121 age- and sex-matched controls of the Turkish population.
|
11757669 |
2001 |
|
Adenocarcinoma of prostate
|
|
0.010 |
GeneticVariation
|
BEFREE |
I105V polymorphism and promoter methylation of the GSTP1 gene in prostate adenocarcinoma.
|
12010858 |
2002 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The GSTP1 Ile(105)Val polymorphism is associated in a dose-dependent fashion with increased survival of patients with advanced colorectal cancer receiving 5-FU/oxaliplatin chemotherapy.
|
12072547 |
2002 |
|
Malignant neoplasm of colon and/or rectum
|
|
0.080 |
GeneticVariation
|
BEFREE |
The GSTP1 Ile(105)Val polymorphism is associated in a dose-dependent fashion with increased survival of patients with advanced colorectal cancer receiving 5-FU/oxaliplatin chemotherapy.
|
12072547 |
2002 |
|
Parkinson Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
We tested for associations between genotypes of GSTM1(homozygous deletion vs. non-deleted), GSTT1(homozygous deletion vs. non-deleted), and GSTP1 (Ile104Val and Ala113Val) and PD in a case-control study of 214 idiopathic PD cases and 330 age- and gender-matched, unrelated controls of Caucasian ethnicity.
|
12524158 |
2003 |
|
Glioma
|
|
0.040 |
GeneticVariation
|
BEFREE |
There was evidence of supermultiplicativity of the joint effect of GSTP1 I105V and CYP2E1 RsaI variants on both glioma and acoustic neuroma, even following adjustment of estimates toward a common prior distribution using hierarchical regression models.
|
12540498 |
2003 |
|
Acoustic Neuroma
|
|
0.010 |
GeneticVariation
|
BEFREE |
There was evidence of supermultiplicativity of the joint effect of GSTP1 I105V and CYP2E1 RsaI variants on both glioma and acoustic neuroma, even following adjustment of estimates toward a common prior distribution using hierarchical regression models.
|
12540498 |
2003 |
|
Schizophrenia
|
|
0.020 |
GeneticVariation
|
BEFREE |
This study is aimed to test the association between the coding sequence functional polymorphism (Ile105Val) of glutathione S-transferase P gene (GSTP1) and schizophrenia in the Korean population.
|
12691788 |
2003 |
|
Childhood Leukemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
The role of methylenetetrahydrofolate reductase (MTHFR C677T), glutathione S-transferases (GSTM1 and GSTT1 null, GSTP1 Ile105Val), and cytochromes p450 (CYP1A1*2A) genotypes in the etiology of childhood leukemia was simultaneously investigated.
|
12827651 |
2003 |
|
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
Trends in the association between urinary ITC and breast cancer were more consistent with homozygous deletion of GSTM1 or GSTT1, the AAgenotype of GSTP1 (A313G), or with the C allele of NADPH quinine oxidoreductase (C609T), although interactions were not statistically significant.
|
12873994 |
2003 |
|
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Trends in the association between urinary ITC and breast cancer were more consistent with homozygous deletion of GSTM1 or GSTT1, the AAgenotype of GSTP1 (A313G), or with the C allele of NADPH quinine oxidoreductase (C609T), although interactions were not statistically significant.
|
12873994 |
2003 |
|
Carotid Atherosclerosis
|
|
0.020 |
GeneticVariation
|
BEFREE |
We assessed the contribution of genetic polymorphisms of glutathione S-transferase M1 ( GSTM1), T1 ( GSTT1), and P1 ( GSTP1, Ile105Val) to carotid atherosclerosis in 40 postmenopausal rheumatoid arthritic (RA) women without histories of smoking.
|
12879272 |
2004 |
|
Sporadic Breast Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
In addition, meta-analyses of data in the literature established the TGFBR1*6A, GSTP I105V, and TP53 R72P polymorphisms, as well as the GSTM1 gene deletion as low-penetrance genetic risk factors of sporadic breast cancer.
|
14683420 |
2004 |
|
Maternal hypertension
|
|
0.010 |
GeneticVariation
|
BEFREE |
We therefore performed an association study of the Ile105Val variant comparing 131 patients with HP and 327 normal pregnant controls in Japan.
|
14719182 |
2003 |
|
Pregnancy associated hypertension
|
|
0.010 |
GeneticVariation
|
BEFREE |
We therefore performed an association study of the Ile105Val variant comparing 131 patients with HP and 327 normal pregnant controls in Japan.
|
14719182 |
2003 |
|
Asthma
|
|
0.100 |
GeneticVariation
|
BEFREE |
These results suggest a significant association between GSTP1 Ile105Val polymorphism and susceptibility to asthma and that the GSTP1 Val105Val genotype may be protective against developing this disease.
|
14748821 |
2004 |