rs1695, GSTP1

N. diseases: 188
Disease: Thrombocytopenia ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Thrombocytopenia
CUI: C0040034
Disease: Thrombocytopenia
0.030 GeneticVariation BEFREE No significant association was found between DPYD*6, GSTP1 ile105val polymorphisms and CAPOX related toxicities except for thrombocytopenia. 31653159 2019
Thrombocytopenia
CUI: C0040034
Disease: Thrombocytopenia
0.030 GeneticVariation BEFREE <i>GSTP1</i> rs1695 showed the smallest p value for hematotoxicity association, and the <sup>105</sup>Ile wild type allele had a significantly higher risk of severe hematotoxicity (neutropenia G4, thrombocytopenia ≥ G3 and anemia ≥ G3) than the <sup>105</sup>Val allele (p=0.00034, odds ratio=5.71 (95% confidence interval:1.77-18.44)). 30038720 2018
Thrombocytopenia
CUI: C0040034
Disease: Thrombocytopenia
0.030 GeneticVariation BEFREE The aim of the study is to evaluate the association between granulocytopenia and thrombocytopenia induced by platinum-based drugs and GSTP1 rs1695 gene polymorphism by meta-analysis. 30238837 2018