|
Lupus Erythematosus, Systemic
|
|
0.850 |
GeneticVariation
|
GWASCAT |
Transancestral mapping and genetic load in systemic lupus erythematosus.
|
28714469 |
2017 |
|
Lupus Erythematosus, Systemic
|
|
0.850 |
GeneticVariation
|
BEFREE |
This study implies that rs10516487 and rs17266594 polymorphisms might contribute to individual susceptibility to SLE and influence the ANA/SSA autoantibody response in SLE patients in Chinese population.
|
21078628 |
2011 |
|
Lupus Erythematosus, Systemic
|
|
0.850 |
GeneticVariation
|
BEFREE |
We selected and identified three SNPs of BANK1 associated with SLE (rs17266594, P = 1.949e-10; OR = 1.380; 95% CI: 1.250-1.525; rs10516487, P = 2.642e-13; OR = 1.317; 95% CI: 1.223-1.417; rs3733197, P = 3.452e-06; OR = 1.193; 95% CI: 1.107-1.286); one SNP of TNFAIP3 associated with SLE (rs2230926, P = 1.502e-12; OR = 1.826; 95% CI: 1.545-2.157).
|
21208380 |
2011 |
|
Lupus Erythematosus, Systemic
|
|
0.850 |
GeneticVariation
|
BEFREE |
The strongest associations with SLE and BANK1 were at rs17266594 (corrected P-value=1.97 x 10(-5), odds ratio (OR)=1.22, 95% CI 1.12-1.34) and rs10516487 (corrected P-value=2.59 x 10(-5), OR=1.22, 95% CI 1.11-1.34).
|
19339986 |
2009 |
|
Lupus Erythematosus, Systemic
|
|
0.850 |
GeneticVariation
|
BEFREE |
To investigate 1 functional (rs17266594) and 2 potentially functional (rs10516487 and rs3733197) BANK1 variants, which were previously identified as systemic lupus erythematosus (SLE) susceptibility markers, to test whether they are associated with rheumatoid arthritis (RA).
|
19180476 |
2009 |
|
Lupus Erythematosus, Systemic
|
|
0.850 |
GeneticVariation
|
BEFREE |
We confirmed the associations of BANK1 and TNFSF4 with SLE in Chinese (BANK1, rs3733197, odds ratio (OR)=0.84, P=0.021; BANK1, rs17266594, OR=0.61, P=4.67 x 10(-9); TNFSF4, rs844648, OR=1.22, P=2.47 x 10(-3); TNFSF4, rs2205960, OR=1.30, P=2.41 x 10(-4)).
|
19357697 |
2009 |
|
Lupus Erythematosus, Systemic
|
|
0.850 |
GeneticVariation
|
GWASDB |
Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus.
|
18204447 |
2008 |
|
Autoimmune Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
This meta-analysis demonstrates that BANK1 rs10516487, rs3733197, and rs17266594 polymorphisms are associated with susceptibility to autoimmune diseases.
|
28466820 |
2017 |
|
Primary Sjögren's syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results indicated that the SNPs (rs2736340, rs13277113) of the FAM167A-BLK region, but not the BANK1 SNPs (rs4522865, rs17266594, and rs10516487), were associated with the development of pSS in Han Chinese.
|
23899688 |
2013 |
|
Encephalitis, St. Louis
|
|
0.010 |
GeneticVariation
|
BEFREE |
This study implies that rs10516487 and rs17266594 polymorphisms might contribute to individual susceptibility to SLE and influence the ANA/SSA autoantibody response in SLE patients in Chinese population.
|
21078628 |
2011 |
|
Psoriasis
|
|
0.010 |
GeneticVariation
|
BEFREE |
This study aimed to determine the association between three functional SNPs of BANK1 (rs10516487, rs17266594 and rs3733197) with psoriasis in Southern Han Chinese population by determining their frequency in 242 patients with psoriasis and 317 healthy individuals.
|
21989138 |
2011 |
|
Systemic Scleroderma
|
|
0.010 |
GeneticVariation
|
BEFREE |
A significant association of the rs10516487 G and rs17266594 T alleles with SSc susceptibility was observed (pooled OR=1.12, 95% CI 1.03 to 1.22; p=0.01 and pooled OR=1.14, 95% CI 1.05 to 1.25; p=0.003, respectively), whereas the rs3733197 genetic variant showed no statistically significant deviation.
|
19815934 |
2010 |
|
Rheumatoid Arthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
We did not find a significant association between RA and the rs10516487 and rs17266594 BANK1 polymorphisms.
|
19180476 |
2009 |