rs174547, FADS2;FADS1

N. diseases: 33
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.830 GeneticVariation BEFREE rs174547 in FADS1 may contribute to the susceptibility of CHD by altering HDL-C and TG levels in Chinese individuals. 22490578 2012
Serum albumin measurement
CUI: C0523465
Disease: Serum albumin measurement
0.700 GeneticVariation GWASDB A genome-wide assessment of variability in human serum metabolism. 23281178 2013
Serum albumin measurement
CUI: C0523465
Disease: Serum albumin measurement
0.700 GeneticVariation GWASDB A genome-wide perspective of genetic variation in human metabolism. 20037589 2010
Triglycerides measurement
CUI: C0202236
Disease: Triglycerides measurement
0.800 GeneticVariation GWASDB Common variants at 30 loci contribute to polygenic dyslipidemia. 19060906 2009
High density lipoprotein measurement
CUI: C0392885
Disease: High density lipoprotein measurement
0.800 GeneticVariation GWASDB Common variants at 30 loci contribute to polygenic dyslipidemia. 19060906 2009
Triglycerides measurement
CUI: C0202236
Disease: Triglycerides measurement
0.800 GeneticVariation GWASCAT Common variants at 30 loci contribute to polygenic dyslipidemia. 19060906 2009
High density lipoprotein measurement
CUI: C0392885
Disease: High density lipoprotein measurement
0.800 GeneticVariation GWASCAT Common variants at 30 loci contribute to polygenic dyslipidemia. 19060906 2009
Serum HDL cholesterol measurement
CUI: C0428472
Disease: Serum HDL cholesterol measurement
0.700 GeneticVariation GWASDB Common variants at 30 loci contribute to polygenic dyslipidemia. 19060906 2009
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.020 GeneticVariation BEFREE Dietary n-3 LCPUFA intakes could modulate the association between FADS1 rs174547 polymorphism and CAD. 25849351 2015
Triglycerides measurement
CUI: C0202236
Disease: Triglycerides measurement
0.800 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
High density lipoprotein measurement
CUI: C0392885
Disease: High density lipoprotein measurement
0.800 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
Low density lipoprotein cholesterol measurement
CUI: C0202117
Disease: Low density lipoprotein cholesterol measurement
0.700 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
Serum total cholesterol measurement
CUI: C1445957
Disease: Serum total cholesterol measurement
0.700 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
Phospholipid measurement
CUI: C0202177
Disease: Phospholipid measurement
0.700 GeneticVariation GWASDB Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. 21829377 2011
RESTING HEART RATE
CUI: C1821417
Disease: RESTING HEART RATE
0.800 GeneticVariation GWASDB Genome-wide association analysis identifies multiple loci related to resting heart rate. 20639392 2010
RESTING HEART RATE
CUI: C1821417
Disease: RESTING HEART RATE
0.800 GeneticVariation GWASCAT Genome-wide association analysis identifies multiple loci related to resting heart rate. 20639392 2010
Lipids measurement
CUI: C0523744
Disease: Lipids measurement
0.800 GeneticVariation GWASCAT Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219 2012
Lipids measurement
CUI: C0523744
Disease: Lipids measurement
0.800 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219 2012
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.830 GeneticVariation GWASDB Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. 21347282 2011
Lipids measurement
CUI: C0523744
Disease: Lipids measurement
0.800 GeneticVariation GWASCAT Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA. 27005778 2016
elevated blood glucose level
CUI: C0495706
Disease: elevated blood glucose level
0.800 GeneticVariation GWASDB Human metabolic individuality in biomedical and pharmaceutical research. 21886157 2011
Glucose measurement
CUI: C0337438
Disease: Glucose measurement
0.800 GeneticVariation GWASDB Human metabolic individuality in biomedical and pharmaceutical research. 21886157 2011
Ischemic stroke
CUI: C0948008
Disease: Ischemic stroke
0.010 GeneticVariation BEFREE In the secondary analysis, the minor allele of rs174547 in <i>FADS1</i> was associated with significantly lower odds of any ischemic stroke, large-artery stroke, and venous thromboembolism and showed suggestive evidence of inverse association with coronary artery disease, abdominal aortic aneurysm and aortic valve stenosis. 31817859 2019
Venous Thromboembolism
CUI: C1861172
Disease: Venous Thromboembolism
0.010 GeneticVariation BEFREE In the secondary analysis, the minor allele of rs174547 in <i>FADS1</i> was associated with significantly lower odds of any ischemic stroke, large-artery stroke, and venous thromboembolism and showed suggestive evidence of inverse association with coronary artery disease, abdominal aortic aneurysm and aortic valve stenosis. 31817859 2019
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.830 GeneticVariation BEFREE In the secondary analysis, the minor allele of rs174547 in <i>FADS1</i> was associated with significantly lower odds of any ischemic stroke, large-artery stroke, and venous thromboembolism and showed suggestive evidence of inverse association with coronary artery disease, abdominal aortic aneurysm and aortic valve stenosis. 31817859 2019