rs174556, FADS2;FADS1

N. diseases: 7
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Fatty acid measurement
CUI: C1281901
Disease: Fatty acid measurement
0.700 GeneticVariation GWASCAT Multiplex genomewide association analysis of breast milk fatty acid composition extends the phenotypic association and potential selection of FADS1 variants to arachidonic acid, a critical infant micronutrient. 29514873 2018
Serum albumin measurement
CUI: C0523465
Disease: Serum albumin measurement
0.700 GeneticVariation GWASDB A genome-wide assessment of variability in human serum metabolism. 23281178 2013
Serum albumin measurement
CUI: C0523465
Disease: Serum albumin measurement
0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219 2012
Phospholipid measurement
CUI: C0202177
Disease: Phospholipid measurement
0.700 GeneticVariation GWASDB Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. 21829377 2011
Triglycerides measurement
CUI: C0202236
Disease: Triglycerides measurement
0.700 GeneticVariation GWASDB A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection. 19074352 2008
Acute Chest Syndrome
CUI: C0742343
Disease: Acute Chest Syndrome
0.010 GeneticVariation BEFREE The trans-phase gene-gene interaction analysis showed that the combined genotype of rs174556 (T/T) and rs3756963 (T/T) was associated with ACS (P = 0.031). 23555103 2013
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.010 GeneticVariation BEFREE And the results suggest that, for rs174556 C>T, the CT/TT genotypes were more likely to lead in ACS in subjects with hypertension after correction of all risk factors (OR = 4.236, 95% CI, 2.216-7.126). 23555103 2013
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.010 GeneticVariation BEFREE The trans phase gene-gene interaction analysis showed that the combined genotype of rs174556 (T/T) and rs3756963 (T/T) was weakly associated with the disease (P=0.043). rs174556 in the FADS1 gene is very likely to be associated with CAD in the Chinese Han population. 21917437 2011