rs17576, MMP9

N. diseases: 73
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Prolapsed lumbar disc
CUI: C0281899
Disease: Prolapsed lumbar disc
0.020 GeneticVariation BEFREE Our results indicated that the A allele of rs17576 reduced the risk of LDH by ∼23% on average. 30289281 2018
Prolapsed lumbar disc
CUI: C0281899
Disease: Prolapsed lumbar disc
0.020 GeneticVariation BEFREE Further, a missense SNP in MMP9 (Q279R; rs17576) is also strongly associated with LDH in the Japanese population (p = 0.00049) and shows a combinatorial effect with THBS2 (odds ratio 3.03, 95% confidence interval 1.58-5.77). 18455130 2008