Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.080 GeneticVariation BEFREE However, we did not observe any association between the colorectal cancer risk and the rs3212986(ERCC1) and rs17655(ERCC5) polymorphisms. 31568607 2019
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.080 GeneticVariation BEFREE In subgroup analysis, the significant association between the rs1</span>7655 C allele and CRC risk was found in Asians and hospital-based subgroups. 30899401 2019
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.080 GeneticVariation BEFREE The Asp1104His polymorphism of ERCC5 was associated with the risk and 5-year survival rate of CRC as well as treatment sensitivity to oxaliplatin. 30517302 2018
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.080 GeneticVariation BEFREE This meta-analysis indicated that the <i>XPG</i> gene rs17655 G>C polymorphism was associated with increased overall cancer risk, especially the risk of gastric cancer and colorectal cancer. 29779017 2018
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.080 GeneticVariation BEFREE This meta-analysis suggests that the ERCC5 rs17655 polymorphism might contribute to genetic susceptibility to colorectal cancer. 26225711 2015
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.080 GeneticVariation BEFREE In conclusion, our findings suggest that XPG Asp1104His polymorphism may increase the susceptibility of CRC, especially in Asian populations. 25332048 2014
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.080 GeneticVariation BEFREE In conclusion, the current data suggested that XPC Lys939Gln and XPG Asp1104His polymorphisms might contribute to the identification of patients with increased risk for CRC. 22213216 2012
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.080 GeneticVariation BEFREE The aim of this study was to investigate the associations between the APE1 Asp148Glu, hOGG1 Ser326Cys, XRCC1 Arg399Gln, XRCC3 Thr241Met, XPD Lys751Gln, XPG Asp1104His polymorphisms and CRC risk in Turkish population. 21561390 2011
Malignant neoplasm of lung
CUI: C0242379
Disease: Malignant neoplasm of lung
0.070 GeneticVariation BEFREE XPC K939Q, XPA 5'UTR, XPG F670W and XPG D1104H had the best ability to predict lung cancer risk (CVC = 100, p < 0.0001). 31195348 2019
Malignant neoplasm of lung
CUI: C0242379
Disease: Malignant neoplasm of lung
0.070 GeneticVariation BEFREE Using the multifactor dimensionality reduction method, we found a model of gene-gene interactions associated with the risk of lung cancer: NBS1 (rs1805794)-XRCC1 (rs25487)-hOGG1 (rs1052133)-XPG (rs17655). 31584889 2019
Primary malignant neoplasm of lung
CUI: C1306460
Disease: Primary malignant neoplasm of lung
0.070 GeneticVariation BEFREE XPC K939Q, XPA 5'UTR, XPG F670W and XPG D1104H had the best ability to predict lung cancer risk (CVC = 100, p < 0.0001). 31195348 2019
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.070 GeneticVariation BEFREE Using the multifactor dimensionality reduction method, we found a model of gene-gene interactions associated with the risk of lung cancer: NBS1 (rs1805794)-XRCC1 (rs25487)-hOGG1 (rs1052133)-XPG (rs17655). 31584889 2019
Primary malignant neoplasm of lung
CUI: C1306460
Disease: Primary malignant neoplasm of lung
0.070 GeneticVariation BEFREE Using the multifactor dimensionality reduction method, we found a model of gene-gene interactions associated with the risk of lung cancer: NBS1 (rs1805794)-XRCC1 (rs25487)-hOGG1 (rs1052133)-XPG (rs17655). 31584889 2019
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.070 GeneticVariation BEFREE XPC K939Q, XPA 5'UTR, XPG F670W and XPG D1104H had the best ability to predict lung cancer risk (CVC = 100, p < 0.0001). 31195348 2019
Primary malignant neoplasm of lung
CUI: C1306460
Disease: Primary malignant neoplasm of lung
0.070 GeneticVariation BEFREE The results from this meta-analysis indicate that the XPG gene Asp1</span>104His polymorphism is associ</span>ated with lung cancer risk, especially in Asians. 27323149 2016
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.070 GeneticVariation BEFREE The results from this meta-analysis indicate that the XPG gene Asp1</span>104His polymorphism is associ</span>ated with lung cancer risk, especially in Asians. 27323149 2016
Malignant neoplasm of lung
CUI: C0242379
Disease: Malignant neoplasm of lung
0.070 GeneticVariation BEFREE The results from this meta-analysis indicate that the XPG gene Asp1</span>104His polymorphism is associ</span>ated with lung cancer risk, especially in Asians. 27323149 2016
Malignant neoplasm of lung
CUI: C0242379
Disease: Malignant neoplasm of lung
0.070 GeneticVariation BEFREE In summary, our meta-analysis suggests that ERCC5 rs17655 polymorphism may not contribute to genetic susceptibility for lung cancer. 24596032 2014
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.070 GeneticVariation BEFREE In summary, our meta-analysis suggests that ERCC5 rs17655 polymorphism may not contribute to genetic susceptibility for lung cancer. 24596032 2014
Primary malignant neoplasm of lung
CUI: C1306460
Disease: Primary malignant neoplasm of lung
0.070 GeneticVariation BEFREE In summary, our meta-analysis suggests that ERCC5 rs17655 polymorphism may not contribute to genetic susceptibility for lung cancer. 24596032 2014
Malignant neoplasm of lung
CUI: C0242379
Disease: Malignant neoplasm of lung
0.070 GeneticVariation BEFREE From MDR analysis, in Latinos, smoking and 3 SNPs (ERCC2 rs171140, ERCC5 rs17655 and LIG1 rs20581) together had a prediction accuracy of 67.4% (p = 0.001) for lung cancer. 18709642 2008
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.070 GeneticVariation BEFREE From MDR analysis, in Latinos, smoking and 3 SNPs (ERCC2 rs171140, ERCC5 rs17655 and LIG1 rs20581) together had a prediction accuracy of 67.4% (p = 0.001) for lung cancer. 18709642 2008
Primary malignant neoplasm of lung
CUI: C1306460
Disease: Primary malignant neoplasm of lung
0.070 GeneticVariation BEFREE From MDR analysis, in Latinos, smoking and 3 SNPs (ERCC2 rs171140, ERCC5 rs17655 and LIG1 rs20581) together had a prediction accuracy of 67.4% (p = 0.001) for lung cancer. 18709642 2008
Primary malignant neoplasm of lung
CUI: C1306460
Disease: Primary malignant neoplasm of lung
0.070 GeneticVariation BEFREE With the adjustment for potential confounders, the XPG Asp1104Asp genotype was inversely associated with lung cancer (odds ratio [OR] = 0.62, 95% confidence limits [CL] = 0.38, 1.0) and SCCOLE (OR = 0.47, 95% CL = 0.27, 0.82), with the combined His1104His and His1104Asp genotypes as the referent. 16094634 2006
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.070 GeneticVariation BEFREE With the adjustment for potential confounders, the XPG Asp1104Asp genotype was inversely associated with lung cancer (odds ratio [OR] = 0.62, 95% confidence limits [CL] = 0.38, 1.0) and SCCOLE (OR = 0.47, 95% CL = 0.27, 0.82), with the combined His1104His and His1104Asp genotypes as the referent. 16094634 2006