|
Monocyte count result
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
Monocyte count procedure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
HIV-1 infection
|
|
0.070 |
GeneticVariation
|
BEFREE |
No association with CCR2b-V64I (17%) and SDF1-3'A (2%) variants was determined in relation to HIV-1 infection in Gabonese patients.
|
25592723 |
2015 |
|
HIV-1 infection
|
|
0.070 |
GeneticVariation
|
BEFREE |
Here, we determined the association of the CCR5 promoter SNPs, the CCR5-Δ32 mutation, CCR2-V64I SNP, and HH frequencies with resistance/susceptibility to HIV-1 infection in a cohort of HIV-1-serodiscordant couples from Colombia.
|
24098976 |
2013 |
|
HIV-1 infection
|
|
0.070 |
GeneticVariation
|
BEFREE |
In addition, we also identified the best three-factor interaction model, including the CCR5 58755-A/G, 59029-A/G, and CCR2-V64I polymorphisms, indicating that there were also strong gene-gene interactions between the CCR5 promoter and CCR2 polymorphisms on the susceptibility of HIV-1 infection.
|
23057571 |
2012 |
|
HIV-1 infection
|
|
0.070 |
GeneticVariation
|
BEFREE |
The meta-analysis clarified that the CCR2-Val64Ile polymorphism has no effect on susceptibility to HIV-1 infection in the total population.
|
21461583 |
2011 |
|
HIV-1 infection
|
|
0.070 |
GeneticVariation
|
BEFREE |
Substitution of V64I in CCR2 relates to delayed progression to AIDS and protects against HIV-1 infection.
|
17504503 |
2007 |
|
HIV-1 infection
|
|
0.070 |
GeneticVariation
|
BEFREE |
Four SNPs (CCR2-V64I, CCR5-2459, MIP1A+954, and IL2+3896) and specific haplotypes in the IL2 and CCR2/CCR5 regions were significantly associated with HIV-1 infection susceptibility in different genetic models.
|
16323127 |
2006 |
|
HIV-1 infection
|
|
0.070 |
GeneticVariation
|
BEFREE |
A single nucleotide polymorphism (SNP) at codon 64 in the CC chemokine receptor 2 gene (CCR2 V64I) has been associated with a dominant effect of delaying disease progression from human immunodeficiency virus-1 (HIV-1) infection to acquired immunodeficiency syndrome (AIDS).
|
12325020 |
2002 |
|
Hepatitis C
|
|
0.040 |
GeneticVariation
|
BEFREE |
Susceptibility to HCV infection is associated with A alleles of both (rs743660 and rs1799864 G/A) of CCR2 while spontaneous clearance of HCV is associated with the C allele of rs13900 of CCL2 and T allele of rs3817655 of CCL5.
|
30175654 |
2019 |
|
Human immunodeficiency virus (HIV) II infection category B1
|
|
0.040 |
GeneticVariation
|
BEFREE |
In a North American, treated, adherent human immunodeficiency virus (HIV)-positive cohort (self-identified whites, n = 175; blacks, n = 218), we investigated whether CYP2B6 (516G>T, 983T>C), UGT2B7 (IVS1+985A>G, 802C>T), MDR1 3435C>T, chemokine (C-C motif) receptor 2 (CCR2) 190G>A, and CCR5 (-2459G>A, Δ32) polymorphisms influenced the time to achieve virologic success (TVLS).
|
21673041 |
2011 |
|
Myocardial Infarction
|
|
0.040 |
GeneticVariation
|
BEFREE |
In the present study, we investigated whether genetic variants of CCR2-V64I and CCR5-delta32 chemokine receptors have any effect on the development of myocardial infarction.
|
20182805 |
2010 |
|
Hepatitis C
|
|
0.040 |
GeneticVariation
|
BEFREE |
CCL2-2518 A/G and CCR2 190 A/G do not influence the outcome of hepatitis C virus infection in the Spanish population.
|
17465499 |
2007 |
|
Myocardial Infarction
|
|
0.040 |
GeneticVariation
|
BEFREE |
In our cohort we were unable to demonstrate a significant association of the MCP-1 -2518A>G, MCP-1 -2076A>T or CCR2 190G>A polymorphisms with MI.
|
16356504 |
2006 |
|
Human immunodeficiency virus (HIV) II infection category B1
|
|
0.040 |
GeneticVariation
|
BEFREE |
Both antiretroviral therapy and the human coreceptor polymorphism CCR2-V64I slow progression of human immunodeficiency virus type 1 (HIV-1) disease.
|
15472820 |
2004 |
|
Hepatitis C
|
|
0.040 |
GeneticVariation
|
BEFREE |
The CCR2-V64I allele was present in 24 of 278 HCV chromosomes (8.6%) and 19 of 200 control chromosomes (9.5%).
|
15230854 |
2004 |
|
Hepatitis C
|
|
0.040 |
GeneticVariation
|
BEFREE |
The G190A polymorphism (variant allele Ile64) in the first transmembrane domain of CCR2 was under-represented in the 29 patients who had cleared the hepatitis C virus spontaneously (P = 0.018).
|
15086398 |
2004 |
|
Myocardial Infarction
|
|
0.040 |
GeneticVariation
|
BEFREE |
If the VI genotype of the CCR2-V64I is indeed a risk factor for an earlier MI onset in females must be checked by independent studies in other centres and/or populations.
|
12853162 |
2003 |
|
Human immunodeficiency virus (HIV) II infection category B1
|
|
0.040 |
GeneticVariation
|
BEFREE |
A single nucleotide polymorphism (SNP) at codon 64 in the CC chemokine receptor 2 gene (CCR2 V64I) has been associated with a dominant effect of delaying disease progression from human immunodeficiency virus-1 (HIV-1) infection to acquired immunodeficiency syndrome (AIDS).
|
12325020 |
2002 |
|
Myocardial Infarction
|
|
0.040 |
GeneticVariation
|
BEFREE |
A total of 214 patients with an age at the first MI episode <55 years, 96 patients that suffered the first MI episode when older than 60 years, and 360 population controls were polymerase chain reaction genotyped for the CCR2-V64I and CCR5-Delta32/wt polymorphisms.
|
11477473 |
2001 |
|
Human immunodeficiency virus (HIV) II infection category B1
|
|
0.040 |
GeneticVariation
|
BEFREE |
Of the 99 HIV-seronegative female workers, 19 (19.2%) were heterozygous for the CCR2b-V64I mutation compared with 37 (23%) of the 161 HIV-seropositive FSW (P = 0.47).
|
11468722 |
2001 |
|
Parkinson Disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
However, CCR2 V64I polymorphism is not correlated with PD risk.
|
31471711 |
2019 |
|
Malignant neoplasm of prostate
|
|
0.030 |
GeneticVariation
|
BEFREE |
However, -2518 (A > G) and CCR2 V64I (G > A) gene polymorphisms were not significantly associated with PCa risk.
|
25266801 |
2015 |
|
Parkinson Disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
In this study, a cohort of 521 PD patients and 556 cases of healthy controls were recruited to investigate the association between the MCP-1 2518A/G (rs1064211) and CCR2 V64I (rs1799864) gene polymorphisms and PD risk in the Chinese population.
|
25370917 |
2015 |
|
Parkinson Disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
In this study, a cohort of 521 PD patients and 556 cases of healthy controls were recruited to investigate the association between the MCP-1 2518A/G (rs1064211) and CCR2 V64I (rs1799864) gene polymorphisms and PD risk in the Chinese population.
|
25370917 |
2015 |