rs1799971, OPRM1

N. diseases: 95
Disease: Drug abuse ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Drug abuse
CUI: C0013146
Disease: Drug abuse
0.020 GeneticVariation BEFREE This study provides a better understanding on the neurobiological mechanisms that may underlie risk of addiction development in carriers of the A118G SNP in <i>OPRM1</i><b>SIGNIFICANCE STATEMENT</b> The pandemic of opioid drug abuse is associated with many socioeconomic burdens. 31109961 2019
Drug abuse
CUI: C0013146
Disease: Drug abuse
0.020 GeneticVariation BEFREE The OPRM1 A118G single nucleotide polymorphism (SNP rs1799971) gene variant encoding the N40D µ-opioid receptor (MOR) has been associated with dependence on opiates and other drugs of abuse but its mechanism is unknown. 31481756 2019