rs1800206, PPARA

N. diseases: 35
Disease: Obesity ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Obesity
CUI: C0028754
Disease: Obesity
0.060 GeneticVariation BEFREE GMDR analysis indicated a significant two-locus model (p=0.0107) involving rs1800206 and abdominal obesity, indicating a potential interaction among rs1800206 and abdominal obesity. 26671228 2016
Obesity
CUI: C0028754
Disease: Obesity
0.060 GeneticVariation BEFREE This study aimed to investigate the association of peroxisome proliferator-activated receptor (PPAR) genes PPARα L162V, PPARγ2 C161T and PPARδ T294C single nucleotide polymorphisms (SNPs) with obesity and metabolic syndrome (Met-S) in a multi-ethnic population in Kampar, Malaysia. 26673968 2015
Obesity
CUI: C0028754
Disease: Obesity
0.060 GeneticVariation BEFREE According to our study, the L162V SNP does not have a strong impact on the pathogenesis of type 2 diabetes or obesity. 18726867 2009
Obesity
CUI: C0028754
Disease: Obesity
0.060 GeneticVariation BEFREE In conclusion, in a relative large-scale study of middle-aged whites we found no evidence of association between the PPARalpha Leu162Val polymorphism and obesity or type 2 diabetes. 17129741 2007
Obesity
CUI: C0028754
Disease: Obesity
0.060 GeneticVariation BEFREE L162V was not associated with obesity, type 2 diabetes mellitus, hypercholesterolemia, or hypertriglyceridemia. 16297361 2005
Obesity
CUI: C0028754
Disease: Obesity
0.060 GeneticVariation BEFREE This study examined the effect a polymorphism (L162V) in the gene for peroxisome proliferator activated receptor (PPAR) alpha in the development of non-insulin-dependent diabetes mellitus (type 2 DM), obesity and hyperlipidaemia. 11409711 2001