rs1800449, LOX

N. diseases: 33
Disease: Keratoconus ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Keratoconus
CUI: C0022578
Disease: Keratoconus
0.030 GeneticVariation BEFREE Our study demonstrated that the LOX rs1800449 genotypes (AA and GA + AA) and allele (A) appears to confer risk for susceptibility to keratoconus. 24502826 2015
Keratoconus
CUI: C0022578
Disease: Keratoconus
0.030 GeneticVariation BEFREE In contrast, our study lacked sufficient evidences to support the association of rs1800449/rs2288393 with keratoconus across populations. 26713757 2015
Keratoconus
CUI: C0022578
Disease: Keratoconus
0.030 GeneticVariation BEFREE Sequencing of LOX exons in a subset of keratoconus patients identified two polymorphisms, rs1800449 and rs2288393, located in LOX transcripts I and II, associated with keratoconus in case-control and family samples with a meta P value of 0.02. 22661479 2012