rs1800629, TNF

N. diseases: 169
Disease: Reticuloendotheliosis, X-linked ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Reticuloendotheliosis, X-linked
CUI: C0035288
Disease: Reticuloendotheliosis, X-linked
0.010 GeneticVariation BEFREE In the present study, we investigated the role of a promoter region polymorphism rs1800629 (-308G>A) in the inflammatory pathway component TNF-α and its effects on the expression of TNF-α and downstream molecules tumor necrosis factor receptor 1 and 2 (TNFR1 and TNFR2), v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA), and interleukin 6 (IL-6) in KC development. 28702675 2017