rs1800764, None

N. diseases: 10
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Mental deterioration
CUI: C0234985
Disease: Mental deterioration
0.020 GeneticVariation BEFREE At the level of genotypic association, we confirmed that the APOE ε4 homozygote significantly accelerated cognitive decline and found that carriers of the ACE rs1800764_C allele were more likely to show cognitive decline than noncarriers, particularly in those without college education. 24863667 2014
Mental deterioration
CUI: C0234985
Disease: Mental deterioration
0.020 GeneticVariation BEFREE A trend was found for treatment with brain-penetrating ACEIs to slow cognitive decline in AD patients with the haplotype rs1800764 (CC): rs4291 (TT) (p = 0.024), and also non-significantly for independent carriers of rs1800764 or rs4291. 24577465 2014