|
Cardiovascular Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
PCR-based genotyping of insertion/deletion (I/D) polymorphism of ACE (rs4646994) and -629C>A of CETP (rs1800775) was carried out in 520 individuals, of whom 160 had CVD+type 2 diabetes mellitus (T2DM), 90 were CVD patients without T2DM, 150 had T2DM with no cardiovascular complications, and 120 were age- and sex-matched healthy controls.
|
21185205 |
2012 |
|
Coronary Arteriosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our findings indicated that CETP rs708272 may be associated with the risk of coronary atherosclerosis and rs1800775 may influence serum HDL-C levels in healthy controls in Chinese.
|
24283500 |
2013 |
|
Coronary Artery Disease
|
|
0.710 |
GeneticVariation
|
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
Coronary Artery Disease
|
|
0.710 |
GeneticVariation
|
BEFREE |
In this study, we investigated the association of two polymorphisms in the CETP, Taq1B (rs708272) and -629C > A (rs1800775), with CAD and lipid levels HDL-C in 662 CAD + cases and 927 controls from the Singapore population comprising Chinese, Malays and Indians.
|
23758630 |
2013 |
|
Coronary heart disease
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
|
21347282 |
2011 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.010 |
GeneticVariation
|
BEFREE |
In addition, the A-allele of rs4783961 was significantly associated with a reduced T2D risk (odds ratio (OR), 0.82; 95% confidence interval (CI), 0.71‒0.96)), and the A-allele of rs1800775 was significantly related to a lowered DKD risk (OR, 0.78; 95% CI, 0.64‒0.96).
|
31597401 |
2019 |
|
Diabetic Nephropathy
|
|
0.010 |
GeneticVariation
|
BEFREE |
In addition, the A-allele of rs4783961 was significantly associated with a reduced T2D risk (odds ratio (OR), 0.82; 95% confidence interval (CI), 0.71‒0.96)), and the A-allele of rs1800775 was significantly related to a lowered DKD risk (OR, 0.78; 95% CI, 0.64‒0.96).
|
31597401 |
2019 |
|
Dyslipidemias
|
|
0.010 |
GeneticVariation
|
BEFREE |
The polymorphism of CETP genes rs708272, rs3764261, rs1800775, rs711752, rs12149545 was closely related to the dyslipidemia in the Xinjiang Uyghur and Kazakh ethnic groups; and the rs708272 T, rs3764261 T, rs711752 A, and rs12149545 A alleles could reduce risk of dyslipidemia in the Uyghur and Kazakh populations, however, the rs1800775 C allele showed risk factors.
|
26694435 |
2015 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.
|
29404214 |
2018 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.
|
18193044 |
2008 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.
|
18193044 |
2008 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.
|
24023260 |
2013 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study.
|
20031564 |
2009 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A common variant association study reveals novel susceptibility loci for low HDL-cholesterol levels in ethnic Arabs.
|
26879886 |
2016 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
|
17463246 |
2007 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study.
|
20031564 |
2009 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation.
|
23696881 |
2013 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Knowledge-driven multi-locus analysis reveals gene-gene interactions influencing HDL cholesterol level in two independent EMR-linked biobanks.
|
21589926 |
2011 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of blood lipids in Indians confirms universality of established variants.
|
30911093 |
2019 |
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
(3) The rs1800775 polymorphism was associated with high fasting blood glucose levels and low high density lipoprotein cholesterol (HDL-C); rs3764261 and rs12149545 polymorphisms were associated with all components of MS except high blood pressure; rs711752 and rs708272 polymorphisms were associated with low HDL-C (all <i>p</i> < 0.05).
|
28629169 |
2017 |
|
Lipids measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.
|
19936222 |
2009 |
|
Metabolic Syndrome X
|
|
0.020 |
GeneticVariation
|
BEFREE |
We discovered two variants within/near the <i>CETP</i> gene-rs1800775 and rs3816117-associated with MetS at genome-wide significance level during replication phase in Indians.
|
31366177 |
2019 |
|
Metabolic Syndrome X
|
|
0.020 |
GeneticVariation
|
BEFREE |
(3) The rs1800775 polymorphism was associated with high fasting blood glucose levels and low high density lipoprotein cholesterol (HDL-C); rs3764261 and rs12149545 polymorphisms were associated with all components of MS except high blood pressure; rs711752 and rs708272 polymorphisms were associated with low HDL-C (all <i>p</i> < 0.05).
|
28629169 |
2017 |