|
Cervix carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
Association of <i>IL-6</i> -174G>C (rs1800795) polymorphism with cervical cancer susceptibility.
|
30135142 |
2018 |
|
Cervix carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
Haploview analysis demonstrated high linkage disequilibrium (LD) between rs2069845, rs2069840, rs1474348 and rs1800795, and 6-locus haplotype analysis identified GACCCA haplotype to be positively associated with increased CC, while GAGGGG haplotype was negatively associated with CC, thus suggesting a protective role for this haplotype in CC.
|
27722983 |
2017 |
|
Malignant tumor of cervix
|
|
0.040 |
GeneticVariation
|
BEFREE |
Haploview analysis demonstrated high linkage disequilibrium (LD) between rs2069845, rs2069840, rs1474348 and rs1800795, and 6-locus haplotype analysis identified GACCCA haplotype to be positively associated with increased CC, while GAGGGG haplotype was negatively associated with CC, thus suggesting a protective role for this haplotype in CC.
|
27722983 |
2017 |
|
Malignant tumor of cervix
|
|
0.040 |
GeneticVariation
|
BEFREE |
Subgroup analysis indicated that rs1800795 was significantly associated with increased risk of cervical cancer, colorectal cancer, breast cancer, prostate cancer, lung cancer, glioma, non-Hodgkin's lymphoma and Hodgkin's lymphoma but not gastric cancer and multiple myeloma.
|
29552316 |
2018 |
|
Coronary Artery Disease
|
|
0.040 |
GeneticVariation
|
BEFREE |
The C allele of rs1800795 within IL-6 gene promoter, rs1800795-tobacco smoking and rs1800795-alcohol drinking interaction were all associated with increased CAD risk.
|
29889576 |
2018 |
|
Malignant tumor of cervix
|
|
0.040 |
GeneticVariation
|
BEFREE |
Our results show that the C genotype of interleukin 6 rs1800795 is associated with higher cervical cancer risk.
|
27777338 |
2017 |
|
Tuberculosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
GG genotypes of rs1800795 in IL-6 was also associated with occurrence of tuberculosis in our patients with TA.
|
28438554 |
2018 |
|
Primary malignant neoplasm
|
|
0.040 |
GeneticVariation
|
BEFREE |
Having a C allele of the rs1800796 IL6 polymorphisms and the GG genotype of the rs1800795 IL6 polymorphisms was associated with a statistically significantly reduced the risk of colon (OR 0.76 95% CI 0.57, 1.00), but not rectal (OR 1.49 95% CI 1.02,2.16) cancer.
|
17694420 |
2007 |
|
Malignant tumor of cervix
|
|
0.040 |
GeneticVariation
|
BEFREE |
Association of <i>IL-6</i> -174G>C (rs1800795) polymorphism with cervical cancer susceptibility.
|
30135142 |
2018 |
|
Malignant Neoplasms
|
|
0.040 |
GeneticVariation
|
BEFREE |
Simultaneously, rs1800795 and rs1800796 were associated with a significantly higher risk of cancer in Asia and Caucasian, rs1800797 was associated with a significantly risk of cancer in Caucasian but not in Asia.
|
29552316 |
2018 |
|
Primary malignant neoplasm
|
|
0.040 |
GeneticVariation
|
BEFREE |
To date, several association studies examining rs1800795 allele frequency and disease risk have reported seemingly conflicting results ranging from no association to association with either the major or minor allele across a spectrum of conditions, including cancer and autoimmune, cardiovascular, infectious, and metabolic diseases.
|
26578807 |
2015 |
|
Coronary Artery Disease
|
|
0.040 |
GeneticVariation
|
BEFREE |
IL-6 174 G>C rs1800795 was associated with CAD risk in a Chinese population.
|
25299085 |
2014 |
|
Tuberculosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
Collectively, this meta-analysis proved that IL-6 rs1800795, IL-18 rs1946518 and IL-18 rs187238 polymorphisms may confer susceptibility to TB, especially for Asians.
|
31676365 |
2020 |
|
Malignant Neoplasms
|
|
0.040 |
GeneticVariation
|
BEFREE |
To date, several association studies examining rs1800795 allele frequency and disease risk have reported seemingly conflicting results ranging from no association to association with either the major or minor allele across a spectrum of conditions, including cancer and autoimmune, cardiovascular, infectious, and metabolic diseases.
|
26578807 |
2015 |
|
Cervix carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
Subgroup analysis indicated that rs1800795 was significantly associated with increased risk of cervical cancer, colorectal cancer, breast cancer, prostate cancer, lung cancer, glioma, non-Hodgkin's lymphoma and Hodgkin's lymphoma but not gastric cancer and multiple myeloma.
|
29552316 |
2018 |
|
Tuberculosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
Collectively, this meta-analysis proved that IL-2 rs2069762, IL-4 rs2243250, IL-6 rs1800795, IL-8 rs4073, IL-10 rs1800871 and IL-10 rs1800896 polymorphisms may confer susceptibility to TB, especially for Asians.
|
31669382 |
2020 |
|
cervical cancer
|
|
0.040 |
GeneticVariation
|
BEFREE |
Subgroup analysis indicated that rs1800795 was significantly associated with increased risk of cervical cancer, colorectal cancer, breast cancer, prostate cancer, lung cancer, glioma, non-Hodgkin's lymphoma and Hodgkin's lymphoma but not gastric cancer and multiple myeloma.
|
29552316 |
2018 |
|
Primary malignant neoplasm
|
|
0.040 |
GeneticVariation
|
BEFREE |
Simultaneously, rs1800795 and rs1800796 were associated with a significantly higher risk of cancer in Asia and Caucasian, rs1800797 was associated with a significantly risk of cancer in Caucasian but not in Asia.
|
29552316 |
2018 |
|
Tuberculosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
Collectively, this meta-analysis proved that IL-6 rs1800795, IL-8 rs4073, IL-10 rs1800871, IL-10 rs1800872 and IL-10 rs1800896 may confer susceptibility to TB.
|
31560754 |
2019 |
|
Cervix carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
Our results show that the C genotype of interleukin 6 rs1800795 is associated with higher cervical cancer risk.
|
27777338 |
2017 |
|
Primary malignant neoplasm
|
|
0.040 |
GeneticVariation
|
BEFREE |
We observed a non-significant association between rs1800795 and overall cancer risk, while rs1800797 was found to have a false positive association with overall risk of cancer.
|
29842912 |
2018 |
|
cervical cancer
|
|
0.040 |
GeneticVariation
|
BEFREE |
Association of <i>IL-6</i> -174G>C (rs1800795) polymorphism with cervical cancer susceptibility.
|
30135142 |
2018 |
|
cervical cancer
|
|
0.040 |
GeneticVariation
|
BEFREE |
Our results show that the C genotype of interleukin 6 rs1800795 is associated with higher cervical cancer risk.
|
27777338 |
2017 |
|
Malignant Neoplasms
|
|
0.040 |
GeneticVariation
|
BEFREE |
Having a C allele of the rs1800796 IL6 polymorphisms and the GG genotype of the rs1800795 IL6 polymorphisms was associated with a statistically significantly reduced the risk of colon (OR 0.76 95% CI 0.57, 1.00), but not rectal (OR 1.49 95% CI 1.02,2.16) cancer.
|
17694420 |
2007 |
|
cervical cancer
|
|
0.040 |
GeneticVariation
|
BEFREE |
Haploview analysis demonstrated high linkage disequilibrium (LD) between rs2069845, rs2069840, rs1474348 and rs1800795, and 6-locus haplotype analysis identified GACCCA haplotype to be positively associated with increased CC, while GAGGGG haplotype was negatively associated with CC, thus suggesting a protective role for this haplotype in CC.
|
27722983 |
2017 |