rs1800896, IL19;IL10

N. diseases: 113
Disease: Malignant neoplasm of prostate ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of prostate
CUI: C0376358
Disease: Malignant neoplasm of prostate
0.030 GeneticVariation BEFREE In conclusion, <i>IL-10</i> gene rs1800896 polymorphism is associated with the decreased risk of PCa. 29029504 2017
Malignant neoplasm of prostate
CUI: C0376358
Disease: Malignant neoplasm of prostate
0.030 GeneticVariation BEFREE Minor alleles of rs2243250 (T) in IL4 (OR = 1.46, 95% CI 1.03-2.08, P-trend = 0.03), rs1800896 (G) in IL10 (OR = 0.77, 95% CI 0.61-0.96, P-trend = 0.02), rs2430561 (A) in IFNG (OR = 1.33, 95% CI 1.02-1.74; P-trend = 0.04), rs3747531 (C) in MSR1 (OR = 0.55, 95% CI 0.32-0.95; P-trend = 0.03), and possibly rs4073 (A) in IL8 (OR = 0.81, 95% CI 0.64-1.01, P-trend = 0.06) were associated with higher- (Gleason 7-10; N = 222), but not lower- (Gleason 2-6; N = 380) grade prostate cancer. 28317149 2017
Malignant neoplasm of prostate
CUI: C0376358
Disease: Malignant neoplasm of prostate
0.030 GeneticVariation BEFREE We found no association between IL-10 gene rs1800896 polymorphism and PCa in overall population (G versus A: OR=1.00, 95%CI=0.91-1.10, P=0.99; AG+GG versus AA: OR=1.18, 95%CI=0.97-1.43, P=0.10; GG versus AA+AG: OR=1.04, 95%CI=0.86-1.26, P=0.67). 21211963 2011