rs1800896, IL19;IL10

N. diseases: 113
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Ischemic stroke
CUI: C0948008
Disease: Ischemic stroke
0.050 GeneticVariation BEFREE In conclusion, our findings indicated that <i>IL-10</i> rs1800896 polymorphism was significantly associated with individual susceptibility to IS, especially for cerebral infarction. 31722572 2020
Ischemic stroke
CUI: C0948008
Disease: Ischemic stroke
0.050 GeneticVariation BEFREE In addition, IL-10 rs1800896 polymorphism was also significantly associated with individual susceptibility to IS, especially for CI. 31446341 2019
Diabetes Mellitus, Non-Insulin-Dependent
0.050 GeneticVariation BEFREE Therefore, this case-control study involving 327 cases (type 2 diabetes patients with proliferative DR (PDR)) and 461 controls (type 2 diabetes patients without DR) was conducted to address the relationship between IL-10 gene rs1800896 polymorphism and risk of PDR in Chinese population. 30890581 2019
Diabetes Mellitus, Non-Insulin-Dependent
0.050 GeneticVariation BEFREE Interleukin-10 -1082A > G (rs1800896) polymorphism is associated with diabetic retinopathy in type 2 diabetes. 29382585 2018
Diabetes Mellitus, Non-Insulin-Dependent
0.050 GeneticVariation BEFREE The -1082A>G polymorphism (rs1800896) in the interleukin-10 (IL10) gene has been associated with type 2 diabetes and diabetic retinopathy, but its relationship with diabetic kidney disease (DKD) is uncertain. 29227971 2017
Ischemic stroke
CUI: C0948008
Disease: Ischemic stroke
0.050 GeneticVariation BEFREE Overall, there was no significant association between IL-10 (-1082 A/G) [rs1800896] and risk of IS under dominant [AA + AG vs. GG], recessive [AA vs. AG + GG], and allelic [G vs.A] models. 27363685 2016
Ischemic stroke
CUI: C0948008
Disease: Ischemic stroke
0.050 GeneticVariation BEFREE The objective of this study was to evaluate the relationship between three polymorphisms; including tumour necrosis alpha (TNFα)-238 GA, interleukin( IL-10)-1028 GA (rs1800896), IL-6-(rs1800795) and ischemic stroke in a Turkish population. 26722564 2015
Diabetes Mellitus, Non-Insulin-Dependent
0.050 GeneticVariation BEFREE To investigate the relationship between the interleukin 10 (IL10) gene single nucleotide polymorphisms (SNP) -1082 G/A (rs1800896), -819 T/C (rs1800871) and -592 A/C (rs1800872) and risk of type 2 diabetes mellitus in a Chinese population. 24758873 2014
Diabetes Mellitus, Non-Insulin-Dependent
0.050 GeneticVariation BEFREE We investigated whether the -1087G/A (rs1800896), -824C/T (rs1800871), -597C/A (rs1800872) IL-10 polymorphisms were associated with type 2 diabetes in a study on a cohort of Italian Caucasians comprising 490 type 2 diabetic and 349 control subjects. 20388104 2010
Ischemic stroke
CUI: C0948008
Disease: Ischemic stroke
0.050 GeneticVariation BEFREE The aim of the study was to evaluate the association of Interleukin-10 (IL-10)-1082 G/A, promoter polymorphism (rs1800896) with ischemic stroke in a South Indian population from Andhra Pradesh. 21030268 2010
Tuberculosis
CUI: C0041296
Disease: Tuberculosis
0.040 GeneticVariation BEFREE Collectively, this meta-analysis proved that IL-2 rs2069762, IL-4 rs2243250, IL-6 rs1800795, IL-8 rs4073, IL-10 rs1800871 and IL-10 rs1800896 polymorphisms may confer susceptibility to TB, especially for Asians. 31669382 2020
Tuberculosis
CUI: C0041296
Disease: Tuberculosis
0.040 GeneticVariation BEFREE Collectively, this meta-analysis proved that IL-6 rs1800795, IL-8 rs4073, IL-10 rs1800871, IL-10 rs1800872 and IL-10 rs1800896 may confer susceptibility to TB. 31560754 2019
Asthma
CUI: C0004096
Disease: Asthma
0.040 GeneticVariation BEFREE IL-10 rs1800896 gene polymorphism was associated with post-bronchiolitis asthma at 11-13 years of age in children hospitalised for bronchiolitis at less than six months of age. 31074014 2019
Diabetic Retinopathy
CUI: C0011884
Disease: Diabetic Retinopathy
0.040 GeneticVariation BEFREE Therefore, this case-control study involving 327 cases (type 2 diabetes patients with proliferative DR (PDR)) and 461 controls (type 2 diabetes patients without DR) was conducted to address the relationship between IL-10 gene rs1800896 polymorphism and risk of PDR in Chinese population. 30890581 2019
Diabetic Retinopathy
CUI: C0011884
Disease: Diabetic Retinopathy
0.040 GeneticVariation BEFREE Interleukin-10 -1082A > G (rs1800896) polymorphism is associated with diabetic retinopathy in type 2 diabetes. 29382585 2018
Diabetic Retinopathy
CUI: C0011884
Disease: Diabetic Retinopathy
0.040 GeneticVariation BEFREE In addition, we also found that the rs1800896 polymorphism was significantly associated with the risk of diabetic retinopathy (DR). 30223288 2018
Hepatitis C
CUI: C0019196
Disease: Hepatitis C
0.040 GeneticVariation BEFREE IL28B (rs8099917 and rs12979860) and IL10 (rs1800896) polymorphisms alone, or in combination, are good predictors of therapeutic response in HCV-3a patients. 29340806 2018
Diabetic Retinopathy
CUI: C0011884
Disease: Diabetic Retinopathy
0.040 GeneticVariation BEFREE The -1082A>G polymorphism (rs1800896) in the interleukin-10 (IL10) gene has been associated with type 2 diabetes and diabetic retinopathy, but its relationship with diabetic kidney disease (DKD) is uncertain. 29227971 2017
Hepatitis C
CUI: C0019196
Disease: Hepatitis C
0.040 GeneticVariation BEFREE IL-10 rs1800896 variant markedly influences the clinical outcome of HCV infection, and is a determinant of the response to HCV treatment. 28391873 2017
Hepatitis C
CUI: C0019196
Disease: Hepatitis C
0.040 GeneticVariation BEFREE The aim of the present study was to investigate the association between polymorphisms in TNF-α -308 G>A (rs1800629), IL-10 -1082 G>A (rs1800896) and -819/-592 (rs1800871/rs1800872) with HCC risk in individuals with HCV. 26890368 2016
Tuberculosis
CUI: C0041296
Disease: Tuberculosis
0.040 GeneticVariation BEFREE In this study, we investigated a possible association between interleukin-10 (IL-10) -1082A⁄G (rs1800896) and interferon (IFN)-gamma +874T/A (rs2430561) promoter polymorphisms and tuberculosis (TB) in the Azeri population of Iran. 27424131 2016
Asthma
CUI: C0004096
Disease: Asthma
0.040 GeneticVariation BEFREE The present study aimed to evaluate the contribution of IL10 promoter A-1082G (rs1800896), T-819C (rs3021097), A-592C (rs1800872) genetic polymorphisms to the risk of asthma in Taiwan. 26546526 2016
Asthma
CUI: C0004096
Disease: Asthma
0.040 GeneticVariation BEFREE This study was conducted to evaluate the association of IL-10 (interleukin 10) and IL-17F (interleukin 17F) promoter polymorphisms (rs1800871, rs1800896 and rs1889570) with asthma and its clinical phenotypes including severity, atopic status, spirometric parameters, and response to treatment in south Indian population. 26108303 2015
Tuberculosis
CUI: C0041296
Disease: Tuberculosis
0.040 GeneticVariation BEFREE Our results suggest that polymorphisms of the IL-10 encoding gene do not play a central role in the development of complications due to BCG vaccination, although the IL10 gene, especially IL10 rs1800896 (-1082G/A) polymorphism, is known to be associated with tuberculosis risk in Europeans and North Americans. 26459526 2015
Asthma
CUI: C0004096
Disease: Asthma
0.040 GeneticVariation BEFREE In logistic regression adjusted for gender, age and atopy, the carriage of allele A (rs1800896) was a significant risk factor for preschool asthma. 24167151 2014