rs1801131, MTHFR

N. diseases: 93
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Liver carcinoma
CUI: C2239176
Disease: Liver carcinoma
0.030 GeneticVariation BEFREE Our findings indicated that the rs1801131 polymorphism may serve as a genetic biomarker of HCC in Asians. 30917367 2019
Liver carcinoma
CUI: C2239176
Disease: Liver carcinoma
0.030 GeneticVariation BEFREE Further subgroup analyses revealed that the rs1801131</span> polymorphism was significantly associated with the likelihood of HCC in Asians with both FEMs (recessive model: <i>P</i> < 0.0001, OR = 0.42, 95% CI 0.29-0.62; allele model: <i>P</i> = 0.004, OR =1.20, 95% CI 1.06-1.35) and random-effect models (recessive model: <i>P</i> = 0.002, OR = 0.47, 95% CI 0.29-0.75). 31282757 2019
Liver carcinoma
CUI: C2239176
Disease: Liver carcinoma
0.030 GeneticVariation BEFREE This study demonstrated that MTHFR polymorphism was associated with HCC occurrence and post-transplant HCC recurrence. rs1801131 mutation A to C is a valuable molecular biomarker for predicting HCC occurrence in Chinese Han population. 29185200 2018