rs1801133, MTHFR

N. diseases: 174
Disease: Hypertensive disease ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.040 GeneticVariation BEFREE Polymorphisms of the genes MTHFR (rs1801133) and APOA5 (rs662799), as well as anemia, are independent risk factors for stroke in Mexicans, together with traditional cardiovascular risk factors such as high triglycerides and high blood pressure. 29398535 2018
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.040 GeneticVariation BEFREE In this study, we sought to determine whether 2 functional variants (rs1801133 and rs13306560) within the MTHFR are associated with hypertension in Mexican-Mestizos. 26022245 2015
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.040 GeneticVariation BEFREE We also observed a significant association of 4 SNPs and the GRS with hypertension (ATP2B1 rs17249754: P = 0.02; CSK rs1378942: P = 0.02; CYP17A1 rs1004467: P = 0.02; MTHFR rs1801133: P = 0.03; GRS: P = 0.0004). 23591986 2013
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.040 GeneticVariation BEFREE Our data also provide moderate confirmatory evidence of association between MTHFR rs1801133 and the development of hypertension. 19330901 2009