rs1801260, CLOCK;TMEM165

N. diseases: 28
Disease: Sleeplessness ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Sleeplessness
CUI: C0917801
Disease: Sleeplessness
0.020 GeneticVariation BEFREE CLOCK rs1801260 gene polymorphism influences circadian behavior in bipolar disorder (BD), with *C carriers showing a delayed sleep onset and worse insomnia. 26204460 2015
Sleeplessness
CUI: C0917801
Disease: Sleeplessness
0.020 GeneticVariation BEFREE A single nucleotide polymorphism (SNP) in the 3' flanking region of CLOCK (3111 T/C; rs1801260) influenced diurnal preference in healthy humans and caused sleep phase delay and insomnia in patients affected by bipolar disorder. 17428266 2008