rs1801274, FCGR2A

N. diseases: 46
Disease: Ulcerative Colitis ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.850 GeneticVariation BEFREE The minor homozygote (CC) of FCGR2A (rs1801274) may contribute to decrease the susceptibility to UC and the TC haplotype formed by FCGR2A (rs1801274 and rs511278) may increase the risk of UC in the Chinese population. 30260678 2018
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.850 GeneticVariation BEFREE This association seemed to be modified by the UC susceptibility locus, rs1801274, a coding variant in the FcγRIIA gene (Pinteraction = 7.00E-05). 28604414 2017
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.850 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908 2017
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.850 GeneticVariation BEFREE This meta-analysis demonstrates that the FCGR2A rs1801274 G-allele confers susceptibility to KD and UC. 27270653 2016
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.850 GeneticVariation BEFREE We confirmed the associations of 10 known UC risk loci in Koreans: rs76418789 in IL23R (combined P = 1.25 × 10), rs4728142 in IRF5 (combined P = 3.17 × 10), rs1830610 near JAK2 (combined P = 2.28 × 10), rs1555791 near TNFRSF14 (combined P = 1.62 × 10), rs880790 between IL10-IL19 (combined P = 3.73 × 10), rs10185424 between IL1R2-IL1R1 (combined P = 1.54 × 10), rs6478108 in TNFSF15 (combined P = 9.28 × 10), rs861857 between UBE2L3-YDJC (combined P = 3.05 × 10), rs1801274 in FCGR2A (discovery P = 1.54 × 10), and rs17085007 between GPR12-USP12 (discovery P = 3.64 × 10). 26398853 2016
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.850 GeneticVariation BEFREE Six CSE-induced genes in DLD-1 cells were located in UC-susceptibility loci, including HSPA6 (rs1801274). 26826017 2016
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.850 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.850 GeneticVariation GWASCAT Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. 21297633 2011
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.850 GeneticVariation GWASDB Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. 21297633 2011
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.850 GeneticVariation GWASDB A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population. 19915573 2009
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.850 GeneticVariation GWASCAT A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population. 19915573 2009