rs1801282, PPARG

N. diseases: 131
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Alzheimer's Disease
CUI: C0002395
Disease: Alzheimer's Disease
0.060 GeneticVariation BEFREE In summary, the present meta-analysis suggests that the PPAR-γ rs1801282 polymorphism may not be associated with genetic susceptibility of AD in general population. 25770052 2015
Alzheimer's Disease
CUI: C0002395
Disease: Alzheimer's Disease
0.060 GeneticVariation BEFREE This meta-analysis has shown that there is a lack of association between the PPARγ Pro12Ala and His447His polymorphisms and AD risk. 26125935 2015
Alzheimer's Disease
CUI: C0002395
Disease: Alzheimer's Disease
0.060 GeneticVariation BEFREE This meta-analysis identified an association between AD and the COMT Val158Met polymorphism in Asians but not in Europeans, but it revealed no association between AD and the PPARγ Pro12Ala polymorphism. 24477323 2014
Alzheimer's Disease
CUI: C0002395
Disease: Alzheimer's Disease
0.060 GeneticVariation BEFREE These findings suggest that the functional PPAR-gamma Pro12Ala polymorphism may modify the age at onset of AD. 19631630 2009
Alzheimer's Disease
CUI: C0002395
Disease: Alzheimer's Disease
0.060 GeneticVariation BEFREE The peroxisome proliferator-activated receptor gamma (PPAR-gamma2) Pro12Ala polymorphism is associated with higher risk for Alzheimer's disease in octogenarians. 17270153 2007
Alzheimer's Disease
CUI: C0002395
Disease: Alzheimer's Disease
0.060 GeneticVariation BEFREE We found that PPARgamma Pro12Ala polymorphism influenced plasma 24S-hydroxycholesterol/ cholesterol ratios in AD patients in that carriers of the Ala allele presented with higher ratios than homozygote carriers of the Pro-allele. 15666037 2005