Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Impaired glucose tolerance
CUI: C0271650
Disease: Impaired glucose tolerance
0.040 GeneticVariation BEFREE The P12A rare g allele was present in 12% patients with normal glucose metabolism, 11% patients with impaired glucose tolerance or impaired fasting glucose, and 35% patients with diabetes (p=0.014). 21877956 2012
Impaired glucose tolerance
CUI: C0271650
Disease: Impaired glucose tolerance
0.040 GeneticVariation BEFREE The proline allele at PPARG P12A increases risk for diabetes in persons with impaired glucose tolerance, an effect modified by body mass index. 17213274 2007
Impaired glucose tolerance
CUI: C0271650
Disease: Impaired glucose tolerance
0.040 GeneticVariation BEFREE Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A and the Pro12Ala substitution of PPARG2 predict the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial. 16804087 2006
Impaired glucose tolerance
CUI: C0271650
Disease: Impaired glucose tolerance
0.040 GeneticVariation BEFREE Allele frequencies of the Pro12Ala missense mutation of PPARgamma2 were not different among Korean subjects with normal glucose tolerance (qAla = 0.045), those with impaired glucose tolerance (qAla = 0.033), and those with diabetes mellitus (qAla = 0.043; P > 0.05). 10843155 2000