rs1805087, MTR

N. diseases: 135
Disease: Prostate carcinoma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Prostate carcinoma
CUI: C0600139
Disease: Prostate carcinoma
0.050 GeneticVariation BEFREE Vitamin B(12), holo-haptocorrin, and the folate-pathway single-nucleotide polymorphisms MTR 2756A>G and SHMT1 1420C>T have been associated with an increased risk of prostate cancer. 20852008 2010
Prostate carcinoma
CUI: C0600139
Disease: Prostate carcinoma
0.050 GeneticVariation BEFREE In a meta-analysis of folate-pathway polymorphisms, MTR 2756A > G (eight studies, OR = 1.06; 95% CI 1.00, 1.12; P = 0.06) and SHMT1 1420C > T (two studies, OR = 1.11; 95% CI 1.00, 1.22; P = 0.05) were positively associated with prostate cancer risk. 23724740 2013
Prostate carcinoma
CUI: C0600139
Disease: Prostate carcinoma
0.050 GeneticVariation BEFREE Thus, the common polymorphism (rs1805087) of <i>METH</i> may be associated with increased prostate cancer risk. 30337500 2018
Prostate carcinoma
CUI: C0600139
Disease: Prostate carcinoma
0.050 GeneticVariation BEFREE Human methionine synthase A2756G polymorphism increases susceptibility to prostate cancer. 30064122 2018
Prostate carcinoma
CUI: C0600139
Disease: Prostate carcinoma
0.050 GeneticVariation BEFREE Genetic polymorphisms in MTHFR (C677T, A1298C), MTR (A2756G) and MTRR (A66G) genes associated with pathological characteristics of prostate cancer in the Ecuadorian population. 23459165 2013