rs1805087, MTR

N. diseases: 135
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Childhood Lymphoma
CUI: C1332979
Disease: Childhood Lymphoma
0.030 GeneticVariation BEFREE The results in this meta-analysis suggest no association between the MS A2756G polymorphism and lymphoma risk; however, the GG homozygous and G alleles could decrease the lymphoma risk in Caucasians. 28742198 2017
Childhood Lymphoma
CUI: C1332979
Disease: Childhood Lymphoma
0.030 GeneticVariation BEFREE Herein we performed a case-control study evaluating the influence of three single nucleotide polymorphisms (SNPs) in XPA, ERCC5 and MTR [rs1800975 (G-4A), rs17655 (Asp1104His) and rs1805087 (A2756G), respectively] in lymphoma risk. 23818366 2013
Childhood Lymphoma
CUI: C1332979
Disease: Childhood Lymphoma
0.030 GeneticVariation BEFREE Our results suggest that the rs1800975, rs17655 and rs1805087 SNPs in DNA repair and synthesis of genes do not seem to play a major role in lymphoma susceptibility. 23818366 2013
Childhood Lymphoma
CUI: C1332979
Disease: Childhood Lymphoma
0.030 GeneticVariation BEFREE We have previously reported associations between lymphoma risk and germline polymorphisms in genes of methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) and methionine synthase (MTR A2756G), finding the genotype other than the MTHFR 677CC/1298AA to confer a half-risk compared to the MTHFR 677CC/1298AA and a 3-fold higher risk with the MTR GG genotype than the AA/AG genotypes. 15551285 2004