rs1805192, PPARG

N. diseases: 121
Disease: Malignant neoplasm of breast ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of breast
CUI: C0006142
Disease: Malignant neoplasm of breast
0.050 GeneticVariation BEFREE The minor allele of rs1800206 and rs1805192 and its interaction were associated with increased BC risk. 28669518 2017
Malignant neoplasm of breast
CUI: C0006142
Disease: Malignant neoplasm of breast
0.050 GeneticVariation BEFREE Pro 12Ala and Ala203Pro polymorphisms did not modify the association between the iAs methylation capacity and BC. 27557380 2016
Malignant neoplasm of breast
CUI: C0006142
Disease: Malignant neoplasm of breast
0.050 GeneticVariation BEFREE The association between mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) and BC risk was positively modified in PPARγ Pro12Ala C carriers. 23866026 2013
Malignant neoplasm of breast
CUI: C0006142
Disease: Malignant neoplasm of breast
0.050 GeneticVariation BEFREE A marginally significant increased risk of breast cancer was observed among women homozygous for the Ala allele of PPARgamma Pro12Ala. 17348446 2007
Malignant neoplasm of breast
CUI: C0006142
Disease: Malignant neoplasm of breast
0.050 GeneticVariation BEFREE No significant association was observed between PPARgamma Pro12Ala polymorphism and either incident breast cancer (odds ratio = 1.08, 95% confidence interval = 0.85-1.38 for Ala allele carriers compared to non-carriers), plasma hormones, plasma cholesterol, BMI, weight gain since age 18 years or waist-to-hip ratio. 12439219 2002