rs1805192, PPARG

N. diseases: 121
Disease: Lipodystrophy ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Lipodystrophy
CUI: C0023787
Disease: Lipodystrophy
0.020 GeneticVariation BEFREE In rare families, loss-of-function (LOF) mutations in PPARG are known to cosegregate with lipodystrophy and insulin resistance; in the general population, the common P12A variant is associated with a decreased risk of type 2 diabetes (T2D). 25157153 2014
Lipodystrophy
CUI: C0023787
Disease: Lipodystrophy
0.020 GeneticVariation BEFREE PPARgamma Pro12Ala SNP has no effect on the risk of developing lipodystrophy in HIV-1-infected patients treated with HAART. 19534662 2009