rs1893592, UBASH3A

N. diseases: 12
Disease: Diabetes Mellitus, Insulin-Dependent ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Insulin-Dependent
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
0.010 GeneticVariation BEFREE This reduction in UBASH3A, as a consequence of the minor allele at rs1893592</span>, resulted in increased secretion of IL-2, a key cytokine that is required for T-cell activation and function but is deficient in some T1D subjects. 29491471 2018