rs1990760, IFIH1

N. diseases: 33
Disease: Autoimmune Diseases ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Autoimmune Diseases
CUI: C0004364
Disease: Autoimmune Diseases
0.040 GeneticVariation BEFREE The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity. 28553952 2017
Autoimmune Diseases
CUI: C0004364
Disease: Autoimmune Diseases
0.040 GeneticVariation BEFREE A common polymorphism in IFIH1 (rs1990760, A946T) confers increased risk for autoimmune disease, including type 1-diabetes (T1D). 28000722 2016
Autoimmune Diseases
CUI: C0004364
Disease: Autoimmune Diseases
0.040 GeneticVariation BEFREE Association of IFIH1 rs1990760 polymorphism with susceptibility to autoimmune diseases: a meta-analysis. 23734776 2013
Autoimmune Diseases
CUI: C0004364
Disease: Autoimmune Diseases
0.040 GeneticVariation BEFREE We confirm a significant contribution of the Ala946Thr IFIH1 polymorphism to organ-specific autoimmune diseases, extending the range of conditions associated with this variant to include Graves' disease. 17535987 2007