|
High density lipoprotein measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
Serum HDL cholesterol measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
Alzheimer's Disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
In summary, there was no significant association detected between ABCA1 R219K, I883M and R1587K polymorphisms and risk for AD.
|
22982414 |
2012 |
|
Alzheimer's Disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
To evaluate the relationship between ABCA1 genetic variants and Alzheimer's disease (AD), independently or in concert with the APOE epsilon4 allele, we examined three ABCA1 polymorphisms located in the coding region (R219K, I883M, and R1587K) and two ABCA1 polymorphisms in the promoter region (C-14T and C-477T) in a group of 372 Spanish AD patients and 440 controls.
|
17510946 |
2007 |
|
Hyperlipidemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
We conducted a cross-sectional study to investigate the effects of the adenosine triphosphate-binding cassette transporter 1 (ABCA1) I883M and lipoprotein lipase (LPL) HindIII polymorphisms on lipid levels in patients with hyperlipidemia.A total of 533 patients were enrolled.
|
28891316 |
2018 |
|
Obesity
|
|
0.010 |
GeneticVariation
|
BEFREE |
The study results suggest that R219K and I883M SNPs of the ABCA1 gene may play a role in susceptibility to obesity in our Egyptian population; the former increases susceptibility and phenotype severity, and the latter is protective.
|
26243156 |
2015 |
|
Arteriosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The present meta-analysis suggested that the ABCA1 R219K and M883I polymorphisms were associated with the susceptibility to AS.
|
24466114 |
2014 |
|
Atherosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The present meta-analysis suggested that the ABCA1 R219K and M883I polymorphisms were associated with the susceptibility to AS.
|
24466114 |
2014 |
|
Myocardial Ischemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
A stepwise regression approach identified V771M, I883M, and E1172D as the most important predictors of IHD and additive effects on IHD risk were present for V771M/I883M and I883M/E1172D pairs.
|
17951323 |
2008 |
|
Carotid Atherosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The I883M variant showed no effect on plasma lipids or carotid atherosclerosis.
|
18803945 |
2008 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of the present study was to investigate the relationship between R219K, M883I, and R1587K variants of the ATP-binding cassette transporter subfamily A number 1 (ABCA1) gene and response to rosiglitazone treatment in newly diagnosed patients with type 2 diabetes.
|
18215356 |
2008 |
|
Myocardial Infarction
|
|
0.010 |
GeneticVariation
|
BEFREE |
We have analysed three polymorphisms of the ABCA1 gene (-477C/T, R219 K, and I883M) in a cohort of young male survivors of myocardial infarction in order to know their influence in long-term prognosis.
|
16313984 |
2006 |
|
Coronary heart disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
We investigated 244 unrelated, consecutively enrolled patients with ischemic stroke, 150 patients with coronary heart disease (CHD) and 193 blood donors for allele frequencies (AFs) of three common ABCA1 polymorphisms (R219K, V771M and I883M).
|
16446539 |
2006 |
|
Coronary Artery Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
While genotype-phenotype associations were not reproduced across populations and loci, V825I and M883I were clearly associated with CAD status in Malays with no effects on HDL-C or apoA1.
|
12709788 |
2003 |