rs2070600, AGER

N. diseases: 82
Disease: Chronic kidney disease stage 5 ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Chronic kidney disease stage 5
CUI: C2316810
Disease: Chronic kidney disease stage 5
0.020 GeneticVariation BEFREE The SNP rs2070600 was strongly associated with sRAGE concentrations and with progression from macroalbuminuria to ESRD. 31127314 2019
Chronic kidney disease stage 5
CUI: C2316810
Disease: Chronic kidney disease stage 5
0.020 GeneticVariation BEFREE Among the three described polymorphisms, only the RAGE Gly82Ser genotype frequency was significantly increased in the group with advanced nephropathy (11%) defined by a chronic renal failure compared to the three others groups: no nephropathy, 5%; incipient (microalbuminuria) 5%; established (macroalbuminuria), 2%) (P=0.04). 15803111 2005