rs2227983, EGFR

N. diseases: 31
Disease: Skin toxicity ×
Source: BEFREE ×
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Skin toxicity
CUI: C1167791
Disease: Skin toxicity
0.020 GeneticVariation BEFREE This pilot study provides preliminary evidence supporting genetic variation of EGFR (rs2227983), KRAS (rs61764370) and FCGR2A (rs180127) as useful biomarkers for predicting reduced skin toxicity in HNSCC patients treated with a cetuximab-based therapy. 27938998 2016
Skin toxicity
CUI: C1167791
Disease: Skin toxicity
0.020 GeneticVariation BEFREE Our study revealed an influence of the EGFR-R521K genotype on skin toxicity and suggested its relation to clinical activity of cetuximab/docetaxel treatment. 20028750 2010