rs2228671, LDLR

N. diseases: 14
Disease: Coronary heart disease ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.730 GeneticVariation BEFREE We concluded that the heterozygosity in LDLR-rs72658855and rs2228671 and T allele in LDLR rs2228671are strongly associated with an increased susceptibility to coronary artery disease. 31613733 2020
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.730 GeneticVariation BEFREE Meta-analysis has established rs2228671 as a protective factor of CHD in Europeans. 24900971 2014
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.730 GeneticVariation GWASDB Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. 21347282 2011
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.730 GeneticVariation BEFREE The aim of this study was to evaluate 3 single nucleotide polymorphisms in SMARCA4-LDLR gene locus (rs1122608, rs2228671, and rs688) and FVIII coagulant activity (FVIII:c) in subjects with (n = 692) or without (n = 291) angiographically confirmed coronary artery disease (CAD). 20810930 2010