rs2231142, ABCG2

N. diseases: 56
Disease: Gout ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Gout
CUI: C0018099
Disease: Gout
0.820 GeneticVariation GWASCAT Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. 31578528 2019
Gout
CUI: C0018099
Disease: Gout
0.820 GeneticVariation GWASCAT Genome-Wide Association and Functional Studies Reveal Novel Pharmacological Mechanisms for Allopurinol. 30924126 2019
Gout
CUI: C0018099
Disease: Gout
0.820 GeneticVariation BEFREE ABCG2 rs2231142 may predict the risk of kidney comorbidities for Chinese Han male gout patients, but not allopurinol response. 31367212 2019
Gout
CUI: C0018099
Disease: Gout
0.820 GeneticVariation GWASCAT ABCG2 contributes to the development of gout and hyperuricemia in a genome-wide association study. 29453348 2018
Gout
CUI: C0018099
Disease: Gout
0.820 GeneticVariation BEFREE The p.Q141K (rs2231142) variant had a significantly higher minor allele frequency (0.23) in the gout patients compared with the European-origin population (0.09) and was significantly more common among gout patients than among normouricaemic controls (odds ratio = 3.26, P < 0.0001). 28968913 2017
Gout
CUI: C0018099
Disease: Gout
0.820 GeneticVariation GWASCAT Genome-wide association analysis identifies three new risk loci for gout arthritis in Han Chinese. 25967671 2015
Gout
CUI: C0018099
Disease: Gout
0.820 GeneticVariation GWASCAT Genome-wide association study identifies ABCG2 (BCRP) as an allopurinol transporter and a determinant of drug response. 25676789 2015
Gout
CUI: C0018099
Disease: Gout
0.820 GeneticVariation GWASDB Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. 23263486 2013
Gout
CUI: C0018099
Disease: Gout
0.820 GeneticVariation GWASDB Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele. 21768215 2011
Gout
CUI: C0018099
Disease: Gout
0.820 GeneticVariation GWASCAT Identification of low-frequency variants associated with gout and serum uric acid levels. 21983786 2011
Gout
CUI: C0018099
Disease: Gout
0.820 GeneticVariation GWASDB Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. 20884846 2010
Gout
CUI: C0018099
Disease: Gout
0.820 GeneticVariation GWASDB Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study. 18834626 2008