|
Intervertebral Disc Degeneration
|
|
0.010 |
GeneticVariation
|
BEFREE |
Fas (rs1800682) and FasL (rs763110) polymorphism were associated with the risk of IVDD and Fas (rs2234767) was correlated to the susceptibility of OA and RA.
|
29734947 |
2018 |
|
Degenerative polyarthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Fas (rs1800682) and FasL (rs763110) polymorphism were associated with the risk of IVDD and Fas (rs2234767) was correlated to the susceptibility of OA and RA.
|
29734947 |
2018 |
|
cervical cancer
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, we did not observe any association between the cervical cancer risk and the rs2234767 and rs1800682 polymorphisms.
|
27790710 |
2017 |
|
Nodular Goiter
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association of the blood serum cytokines' rate and lymphocytes' apoptosis with polymorphic variants of the BCL-2 (rs17759659), CTLA-4 (rs231775) and APO-1÷FAS (rs2234767) genes in patients with nodular goiters in autoimmune thyroiditis and thyroid adenoma.
|
29250672 |
2017 |
|
Thyroid Gland Follicular Adenoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association of the blood serum cytokines' rate and lymphocytes' apoptosis with polymorphic variants of the BCL-2 (rs17759659), CTLA-4 (rs231775) and APO-1÷FAS (rs2234767) genes in patients with nodular goiters in autoimmune thyroiditis and thyroid adenoma.
|
29250672 |
2017 |
|
Hashimoto Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association of the blood serum cytokines' rate and lymphocytes' apoptosis with polymorphic variants of the BCL-2 (rs17759659), CTLA-4 (rs231775) and APO-1÷FAS (rs2234767) genes in patients with nodular goiters in autoimmune thyroiditis and thyroid adenoma.
|
29250672 |
2017 |
|
Autoimmune thyroiditis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association of the blood serum cytokines' rate and lymphocytes' apoptosis with polymorphic variants of the BCL-2 (rs17759659), CTLA-4 (rs231775) and APO-1÷FAS (rs2234767) genes in patients with nodular goiters in autoimmune thyroiditis and thyroid adenoma.
|
29250672 |
2017 |
|
Cervix carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, we did not observe any association between the cervical cancer risk and the rs2234767 and rs1800682 polymorphisms.
|
27790710 |
2017 |
|
Malignant tumor of cervix
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, we did not observe any association between the cervical cancer risk and the rs2234767 and rs1800682 polymorphisms.
|
27790710 |
2017 |
|
Malignant neoplasm of colon and/or rectum
|
|
0.010 |
GeneticVariation
|
BEFREE |
FAS rs2234767 and rs1800682 polymorphisms jointly contributed to risk of colorectal cancer by affecting SP1/STAT1 complex recruitment to chromatin.
|
26759270 |
2016 |
|
Multiple tumors
|
|
0.010 |
GeneticVariation
|
BEFREE |
FAS rs2234767 (-1377 G>A), rs1800682 (-670 A>G) and FASLG rs763110 (-844 C>T) promoter polymorphisms can influence transcriptional activities of the genes and thus multiple tumors susceptibility.
|
26759270 |
2016 |
|
Colorectal Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
In conclusion, the FAS rs2234767 and rs1800682 polymorphisms were in high LD with each other, and they jointly contributed to an increased risk of CRC by altering recruitment of SP1/STAT1 complex to the FAS promoter for transcriptional activation.
|
26759270 |
2016 |
|
Esophageal carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The case-control study aims to investigate the association of Fas and FasL genetic polymorphisms (Fas-670A/G (rs1800682), Fas-1377G/A (rs2234767) and FasL-844T/C (rs763110)) with esophageal carcinoma susceptibility in a north Chinese population.
|
26819081 |
2016 |
|
Stage IIA Gallbladder Cancer AJCC v8
|
|
0.010 |
GeneticVariation
|
BEFREE |
Hence, the present study aimed to investigate the association of functional SNPs of DR4 (rs20575, rs20576 and rs6557634), FAS (rs2234767) and FASL (rs763110) with gallbladder cancer (GBC) risk.
|
24587306 |
2014 |
|
Stage 0 Gallbladder Cancer AJCC v8
|
|
0.010 |
GeneticVariation
|
BEFREE |
Hence, the present study aimed to investigate the association of functional SNPs of DR4 (rs20575, rs20576 and rs6557634), FAS (rs2234767) and FASL (rs763110) with gallbladder cancer (GBC) risk.
|
24587306 |
2014 |
|
Stage IV Gallbladder Cancer AJCC v8
|
|
0.010 |
GeneticVariation
|
BEFREE |
Hence, the present study aimed to investigate the association of functional SNPs of DR4 (rs20575, rs20576 and rs6557634), FAS (rs2234767) and FASL (rs763110) with gallbladder cancer (GBC) risk.
|
24587306 |
2014 |
|
Stage III Gallbladder Cancer AJCC v8
|
|
0.010 |
GeneticVariation
|
BEFREE |
Hence, the present study aimed to investigate the association of functional SNPs of DR4 (rs20575, rs20576 and rs6557634), FAS (rs2234767) and FASL (rs763110) with gallbladder cancer (GBC) risk.
|
24587306 |
2014 |
|
Gallbladder Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Hence, the present study aimed to investigate the association of functional SNPs of DR4 (rs20575, rs20576 and rs6557634), FAS (rs2234767) and FASL (rs763110) with gallbladder cancer (GBC) risk.
|
24587306 |
2014 |
|
Malignant neoplasm of gallbladder
|
|
0.010 |
GeneticVariation
|
BEFREE |
Hence, the present study aimed to investigate the association of functional SNPs of DR4 (rs20575, rs20576 and rs6557634), FAS (rs2234767) and FASL (rs763110) with gallbladder cancer (GBC) risk.
|
24587306 |
2014 |
|
Stage IIB Gallbladder Cancer AJCC v8
|
|
0.010 |
GeneticVariation
|
BEFREE |
Hence, the present study aimed to investigate the association of functional SNPs of DR4 (rs20575, rs20576 and rs6557634), FAS (rs2234767) and FASL (rs763110) with gallbladder cancer (GBC) risk.
|
24587306 |
2014 |
|
Lupus Erythematosus, Systemic
|
|
0.010 |
GeneticVariation
|
BEFREE |
The Fas gene polymorphisms -670A/G (rs1800682) and -1377G/A (rs2234767) have been shown to be associated with systemic lupus erythematosus (SLE), but findings are not consistent.
|
23065220 |
2013 |
|
Acute Promyelocytic Leukemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
We investigated a common G > A polymorphism at position -1377 (rs2234767) in the core promoter of the CD95 cell death receptor gene in 708 subjects with acute myeloid leukemia, including 231 patients with APL.
|
22084312 |
2012 |
|
Squamous cell carcinoma of esophagus
|
|
0.010 |
GeneticVariation
|
BEFREE |
Haplotype analysis indicated that the FAS polymorphisms -670 A > G (rs1800682) and -1377 G > A (rs2234767) were both associated with OSCC in the Mixed Ancestry population (P = 0.006 and P = 0.004, respectively), as well as the CASP8 (-652 6Ndel:302His) haplotype (P = 0.0013).
|
21926110 |
2011 |
|
Rheumatoid Arthritis
|
|
0.020 |
GeneticVariation
|
BEFREE |
Fas (rs1800682) and FasL (rs763110) polymorphism were associated with the risk of IVDD and Fas (rs2234767) was correlated to the susceptibility of OA and RA.
|
29734947 |
2018 |
|
Rheumatoid Arthritis
|
|
0.020 |
GeneticVariation
|
BEFREE |
In conclusion, this study demonstrated that Fas rs2234767 G/A and Bcl2 rs17757541 T/C polymorphisms might be associated with an increased risk of RA.
|
26905515 |
2016 |