rs2249825, HMGB1

N. diseases: 23
Disease: Carcinoma of lung ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.020 GeneticVariation BEFREE We found that the CT or CC+CT heterozygotes of the <i>HMGB1</i> rs1045411 polymorphism reduced the risks for lung cancer, while the G/T/C haplotypes of three <i>HMGB1</i> SNPs (rs1360485, rs1045411 and rs2249825) also reduced the risk for lung cancer by almost half (0.486-fold). 29104475 2017
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.020 GeneticVariation BEFREE The HMGB1 SNPs (rs1412125 and rs2249825) were associated with platinum-based chemotherapy responses in Chinese lung cancer patients. 24684392 2014