rs2266780, FMO3

N. diseases: 9
Disease: Multiple polyps ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Multiple polyps
CUI: C0334108
Disease: Multiple polyps
0.020 GeneticVariation BEFREE These results suggest that combined polymorphic changes in the E158K and E308G alleles may protect against polyposis in patients with FAP treated with sulindac. 16214918 2005
Multiple polyps
CUI: C0334108
Disease: Multiple polyps
0.020 GeneticVariation BEFREE Polymorphisms in FMO3, particularly at the E158K and E308G loci, may reduce activity in catabolizing sulindac and result in an increased efficacy to prevent polyposis in FAP. 15623613 2004