rs2274223, PLCE1

N. diseases: 40
Disease: Giant Cell Arteritis ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Giant Cell Arteritis
CUI: C0039483
Disease: Giant Cell Arteritis
0.020 GeneticVariation BEFREE The association was more prominent for rs2274223 in female (OR = 1.86, 95% CI: 1.49-2.32) and gastric cardia adenocarcinoma (GCA) (OR = 1.71, 95% CI: 1.49-1.95). 21427165 2011
Giant Cell Arteritis
CUI: C0039483
Disease: Giant Cell Arteritis
0.020 GeneticVariation BEFREE A single nucleotide polymorphism (SNP, rs2274223) in PLCE1 has been identified as a novel susceptibility locus in genome-wide association studies (GWAS) of esophageal squamous cell carcinoma (ESCC) and gastric cardia adenocarcinoma (GCA) that share similar risk factors with SCCHN. 21689432 2011