|
Glioma
|
|
0.820 |
GeneticVariation
|
GWASCAT |
Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21.
|
29743610 |
2018 |
|
Glioma
|
|
0.820 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.
|
28346443 |
2017 |
|
Glioma
|
|
0.820 |
GeneticVariation
|
BEFREE |
This meta-analysis demonstrates that the RTEL1 rs2297440 polymorphism plays a moderate, but significant role in the risk of gli</span>oma.
|
26939676 |
2016 |
|
Glioma
|
|
0.820 |
GeneticVariation
|
BEFREE |
Two single variants, the genotypes of "GG" of rs6010620 and "CC" of rs2297440</span> (rs6010620 and rs2297440) in the RTEL1 gene, together with two haplotypes of GCT and ATT, were identified to be associated with glioma development.
|
23683922 |
2013 |
|
Glioma
|
|
0.820 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies five susceptibility loci for glioma.
|
19578367 |
2009 |
|
Glioblastoma
|
|
0.730 |
GeneticVariation
|
GWASCAT |
Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age.
|
30152087 |
2018 |
|
Glioblastoma Multiforme
|
|
0.730 |
GeneticVariation
|
GWASCAT |
Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age.
|
30152087 |
2018 |
|
Glioblastoma Multiforme
|
|
0.730 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.
|
28346443 |
2017 |
|
Glioblastoma
|
|
0.730 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.
|
28346443 |
2017 |
|
Glioblastoma Multiforme
|
|
0.730 |
GeneticVariation
|
BEFREE |
Using the χ(2) test, we found that rs2297440 and rs6010620 in RTEL1 increased risk of GBM.
|
26156397 |
2015 |
|
Glioblastoma
|
|
0.730 |
GeneticVariation
|
BEFREE |
Using the χ(2) test, we found that rs2297440 and rs6010620 in RTEL1 increased risk of GBM.
|
26156397 |
2015 |
|
Glioblastoma
|
|
0.730 |
GeneticVariation
|
BEFREE |
The opposite is true of RTEL (20q13) region polymorphisms, which are significantly associated with glioblastoma (rs2297440, OR = 0.56, P = 4.6 × 10(-10)) but not oligodendroglial tumor.
|
21356187 |
2011 |
|
Glioblastoma Multiforme
|
|
0.730 |
GeneticVariation
|
BEFREE |
The opposite is true of RTEL (20q13) region polymorphisms, which are significantly associated with glioblastoma (rs2297440, OR = 0.56, P = 4.6 × 10(-10)) but not oligodendroglial tumor.
|
21356187 |
2011 |
|
Glioblastoma
|
|
0.730 |
GeneticVariation
|
BEFREE |
We identified LIG4 rs7325927 and BTBD2 rs11670188 as predictors of STS in GBM and CCDC26 rs10464870 and rs891835, HMGA2 rs1563834, and RTEL1 rs2297440 as predictors of LTS.
|
20368557 |
2010 |
|
Glioblastoma Multiforme
|
|
0.730 |
GeneticVariation
|
BEFREE |
We identified LIG4 rs7325927 and BTBD2 rs11670188 as predictors of STS in GBM and CCDC26 rs10464870 and rs891835, HMGA2 rs1563834, and RTEL1 rs2297440 as predictors of LTS.
|
20368557 |
2010 |
|
Central Nervous System Neoplasms
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.
|
28346443 |
2017 |
|
Astrocytoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Moreover, the stratified analyses showed a decreased risk of astrocytoma associated with RTEL1 rs6089953, rs6010620 and rs2297440 (p trend = 0.022, p trend = 0.042, p trend = 0.029, respectively) as well as an increased risk of this subtype associated with RTEL1 rs4809324 (p trend = 0.033).
|
26014354 |
2015 |
|
Childhood Astrocytoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Moreover, the stratified analyses showed a decreased risk of astrocytoma associated with RTEL1 rs6089953, rs6010620 and rs2297440 (p trend = 0.022, p trend = 0.042, p trend = 0.029, respectively) as well as an increased risk of this subtype associated with RTEL1 rs4809324 (p trend = 0.033).
|
26014354 |
2015 |
|
Astrocytoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
In the recessive model, we found two tSNPs (rs2297440 and rs6010620) associated with increased astrocytoma risk.
|
23812731 |
2013 |
|
Childhood Astrocytoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
In the recessive model, we found two tSNPs (rs2297440 and rs6010620) associated with increased astrocytoma risk.
|
23812731 |
2013 |
|
Oligodendroglial Neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
The opposite is true of RTEL (20q13) region polymorphisms, which are significantly associated with glioblastoma (rs2297440, OR = 0.56, P = 4.6 × 10(-10)) but not oligodendroglial tumor.
|
21356187 |
2011 |
|
Childhood Glioblastoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The opposite is true of RTEL (20q13) region polymorphisms, which are significantly associated with glioblastoma (rs2297440, OR = 0.56, P = 4.6 × 10(-10)) but not oligodendroglial tumor.
|
21356187 |
2011 |
|
Adult Oligodendroglial Tumor
|
|
0.010 |
GeneticVariation
|
BEFREE |
The opposite is true of RTEL (20q13) region polymorphisms, which are significantly associated with glioblastoma (rs2297440, OR = 0.56, P = 4.6 × 10(-10)) but not oligodendroglial tumor.
|
21356187 |
2011 |
|
Adult Glioblastoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The opposite is true of RTEL (20q13) region polymorphisms, which are significantly associated with glioblastoma (rs2297440, OR = 0.56, P = 4.6 × 10(-10)) but not oligodendroglial tumor.
|
21356187 |
2011 |