rs231775, CTLA4

N. diseases: 115
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Celiac Disease
CUI: C0007570
Disease: Celiac Disease
0.030 GeneticVariation BEFREE Polymorphisms in the TNF-α(rs1800629), CTLA-4 (rs231775), and PTPN22 (rs2476601) genes have been previous associated with T1D; however, there is no consensus regarding their role in T1D and scarce literature focusing on AIDT and/or CD. 26782543 2015
Celiac Disease
CUI: C0007570
Disease: Celiac Disease
0.030 GeneticVariation BEFREE In the present work, we investigate the possible implication of the CTLA-4 region as a genetic risk factor for CD, through two statistical approaches: the maximum likelihood score (MLS) test in a large Italian sample of affected sib-pairs using polymorphic genetic markers on chromosome 2, and the transmission disequilibrium test (TDT) in continental Italian and Tunisian families using the CTLA-4 exon 1 49 A/G polymorphism. 10599894 1999
Celiac Disease
CUI: C0007570
Disease: Celiac Disease
0.030 GeneticVariation BEFREE To investigate CTLA-4 exon 1 polymorphism (position 49 A/G) in patients with coeliac disease. 10189842 1998