rs231775, CTLA4

N. diseases: 115
Disease: Sepsis ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Sepsis
CUI: C0243026
Disease: Sepsis
0.020 GeneticVariation BEFREE A recent study by our working group revealed that the rs231775 single nucleotide polymorphism (SNP) in the CTLA-4 gene was associated with the survival of patients with sepsis and served as an independent prognostic variable. 30634576 2019
Sepsis
CUI: C0243026
Disease: Sepsis
0.020 GeneticVariation BEFREE In conclusion, our study provides the first evidence for CTLA-4 rs231775 as a prognostic variable for the survival of patients with sepsis and emphasizes the need for further research to reveal potential functional associations between CTLA-4 and the immune pathophysiology of sepsis. 30310101 2018