Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Clear-cell metastatic renal cell carcinoma
0.020 GeneticVariation BEFREE No significant associations with PFS were found.<b>Conclusions:</b> The G-allele of rs231775 in the <i>CTLA-4</i> gene is associated with an improved OS in sunitinib-treated cc-mRCC patients and could potentially be used as a prognostic biomarker.<i></i>. 29490989 2018
Clear-cell metastatic renal cell carcinoma
0.020 GeneticVariation BEFREE The CTLA-4c.49A>G[A]/CTLA-4g.319C>T[C]/CT60[A]/Jo31[T]/CD28c.17+3T>C[T]/ CD28c.1042G>A[G] haplotype was associated with an approximately threefold increased risk of primary tumor necrosis in CCRCC patients (P corrected = 0.0000007) and with the advanced stage of disease (IV) (P corrected = 0.001). 26403483 2015